Evidence map›Paper›PMID 39375236›Full record

SynthesisCardiovascular and interventional radiology2024

Comparative Analysis of Transradial and Transfemoral Approaches in Transarterial Radioembolization for Liver Tumors: A Systematic Review and Meta-Analysis.

Hatem Abdelmoneim Eldeeb, Mahmoud Shaaban Abdelgalil, Asem Ahmed Ghalwash, Asmaa Elganady, Ruaa Mustafa Qafesha, Ibraheem M Alkhawaldeh, Mahmoud Diaa Hindawi, Jaber H Jaradat, Shabaan Mohamed Abduljalil, Hussien Ahmed H Abdelgawad

Abstract readSystematic ReviewMeta-AnalysisComparative Study
In one paragraph

Synthesis in Cardiovascular and interventional radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. A Personal Commentary Regarding Radial and Femoral Arterial Access.Cardiovascular and interventional radiology · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hatem Abdelmoneim EldeebFaculty of Medicine, Alazhar University, Cairo, Egypt.ORCID http://orcid.org/0000-0001-6270-3180
Mahmoud Shaaban AbdelgalilFaculty of Medicine, Ain-Shams University, 359 Abd Allah Nadim Street, Cairo, Egypt. 29908068800596@med.asu.edu.eg.ORCID http://orcid.org/0000-0002-7325-0129
Asem Ahmed GhalwashFaculty of Medicine, Al Azhar University, Cairo, Egypt.ORCID http://orcid.org/0009-0004-0898-6764
Asmaa ElganadyFaculty of Medicine, Alexandria University, Alexandria, Egypt.ORCID http://orcid.org/0000-0001-9717-4688
Ruaa Mustafa QafeshaFaculty of Medicine, Al-Quds University, Jerusalem, Palestine.ORCID http://orcid.org/0000-0002-8745-0260
Ibraheem M AlkhawaldehFaculty of Medicine, Mutah University, Al-Karak, Jordan.ORCID http://orcid.org/0000-0002-0187-1583
Mahmoud Diaa HindawiFaculty of Medicine, Al Azhar University, Cairo, Egypt.ORCID http://orcid.org/0009-0001-3085-6665
Jaber H JaradatFaculty of Medicine, Mutah University, Al-Karak, Jordan.ORCID http://orcid.org/0000-0002-6488-4664
Shabaan Mohamed AbduljalilEradah Complex and Mental Health Hospital, Najran, Kingdom of Saudi Arabia.
Hussien Ahmed H AbdelgawadMedical Research Group of Egypt, Negida Academy, Arlington, MA, USA.ORCID http://orcid.org/0000-0001-7101-837X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTransarterial radioembolization (TARE) is a minimally invasive therapy combining embolization and radiation for cancer treatment. This meta-analysis compares radiation exposure, quality of life, and safety of the transradial (TRA) versus transfemoral (TFA) approaches in TARE for liver tumors. MATERIALS AND

methodsWe searched PubMed, SCOPUS, Cochrane, EMBASE, and Web of Science for studies comparing TRA versus TFA in TARE for liver tumors. Our primary outcomes focused on various measures of patient radiation exposure, including procedure time, fluoroscopy time, air kerma, and dose-area product (DAP). For secondary outcomes, we evaluated safety parameters, such as overall pain experienced during the procedure, pain in the recovery room post-procedure, the incidence of adverse events, and the impact on quality of life. Study quality was assessed using Cochrane's ROB 2 tool for RCTs and the Newcastle-Ottawa scale for observational studies. Data analysis was conducted with REVMAN 5.4.1 software.

resultsSix studies, comprising one RCT and five cohort studies with 1,209 patients, underwent comprehensive analysis. The aggregated findings revealed a significant reduction in procedure duration associated with TRA (MD =- 6.30, 95% CI [- 9.88, - 2.73], P = 0.005). However, no statistically significant differences were found between TRA and TFA groups concerning fluoroscopy time, recovery time, air kerma, DAP, pain in the recovery room, overall pain during the procedure, quality of life measuring mental health and physical function or adverse events.

conclusionTRA and TFA showed comparable results in TARE for liver tumors, but TRA offered a shorter procedure time. Further RCTs with larger samples are needed to confirm these findings. Future studies should assess long-term efficacy for a more complete evaluation.

Indexed as

Embolization, TherapeuticFemoral ArteryLiver NeoplasmsRadial ArteryHumansQuality of LifeLiver tumorsMeta-analysisTransarterial radioembolizationTransfemoralTransradial

Identifiers

PMID39375236
PMCPMC11621202

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.