Evidence map›Paper›PMID 39375058›Full record

ArticleJournal of gastric cancer2024

Association of Soy Foods With Gastric Cancer Considering

Su Youn Nam, Seong Woo Jeon, Joong Goo Kwon, Yun Jin Chung, Yong Hwan Kwon, Si Hyung Lee, Ju Yup Lee, Chang Hun Yang, Junwoo Jo

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Journal of gastric cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03046745 (Analysis and Prediction of Epidemiology and Molecular Biologic Risks of Gastric Cancer by Multicenter Registry), which is not on this map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03046745 unknown statusnot on this map

Analysis and Prediction of Epidemiology and Molecular Biologic Risks of Gastric Cancer by Multicenter Registry

TypeobservationalSponsorKyungpook National University HospitalRan2016 to 2022Enrolled9,000ConditionsGastric Cancer
3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Su Youn NamDepartment of Gastroenterology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID 0000-0002-5568-7714
Seong Woo JeonDepartment of Gastroenterology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea. swjeon@knu.ac.kr.ORCID 0000-0002-9539-9389
Joong Goo KwonDepartment of Internal Medicine, Daegu Catholic University School of Medicine, Daegu, Korea.ORCID 0000-0003-3392-785X
Yun Jin ChungDepartment of Internal Medicine, Daegu Fatima Hospital, Daegu, Korea.ORCID 0000-0002-3622-9216
Yong Hwan KwonDepartment of Gastroenterology, Kyungpook National University Chilgok Hospital, School of Medicine, Kyungpook National University, Daegu, Korea.ORCID 0000-0002-0520-9685
Si Hyung LeeDepartment of Internal Medicine, Yeungnam University School of Medicine, Daegu, Korea.ORCID 0000-0001-7221-7506
Ju Yup LeeDepartment of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea.ORCID 0000-0003-0021-5354
Chang Hun YangDepartment of Internal Medicine, Dongguk University College of Medicine, Gyeongju, Korea.ORCID 0000-0003-4036-2981
Junwoo JoDepartment of Statistics, Kyungpook National University, Daegu, Korea.ORCID 0000-0002-5611-0714

Funding

MOHW 1631100
6 · The paper itself

Abstract

purposeThis study aims to explore the relationship between soy food consumption and gastric cancer (GC) risk, accounting for MATERIALS AND

methodsWe analyzed data from patients with GC and healthy individuals prospectively enrolled by 6 hospitals between 2016 and 2018. Dietary intake was evaluated using questionnaires that categorized seven dietary habits and 19 food groups. Multivariate logistic regression models were applied to examine associations. Model I adjusted for various epidemiological factors, while Model II included further adjustments for

resultsA total of 5,535 participants were included, with 1,629 diagnosed with GC. In Model I, the frequency of soybean/tofu consumption was inversely related to GC risk; adjusted odd ratios (aORs) were 0.62 (95% confidence interval [CI], 0.48-0.8), 0.38 (95% CI, 0.3-0.49), 0.42 (95% CI, 0.33-0.53), and 0.33 (95% CI, 0.27-0.42) for 1 time/week, 2 times/week, 3 times/week, and ≥4 times/week. Consumption of 2 servings/week of soybean paste stew showed the lowest GC association, forming a V-shaped curve. Both low (aOR, 4.03; 95% CI, 3.09-5.26) and high serving frequencies of soybean paste stew (aOR, 2.23; 95% CI, 1.76-2.82) were associated with GC. The association between soy foods and GC in Model II was similar to that in Model I. The soy food-GC associations were consistent across sexes in Model I. Nonetheless, the positive correlation between frequent consumption of soybean paste stew (≥5 times/week) and GC was more pronounced in women (aOR, 7.58; 95% CI, 3.20-17.99) compared to men (aOR, 3.03; 95% CI, 1.61-5.88) in Model II. Subgroup analyses by

conclusionsSoybean/tofu intake is consistently associated with a decreased risk of GC. However, the relationship between soybean paste stew consumption and GC risk varies, depending on

trial registrationClinicalTrials.gov Identifier: NCT03046745.

Indexed as

Helicobacter InfectionsHelicobacter pyloriSoy FoodsStomach NeoplasmsAdultAgedCase-Control StudiesFeeding BehaviorFemaleHumansMaleMiddle AgedProspective StudiesRisk FactorsGastric cancerHelicobacter pyloriSoy beans

Identifiers

PMID39375058
PMCPMC11471324

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.