Evidence map›Paper›PMID 39374899›Full record

Trial reportJournal of substance use and addiction treatment2025

Improvement in coping skills from culturally-adapted digital CBT for Spanish-speaking Hispanics with substance use disorder: Secondary analysis of a randomized clinical trial.

Bryan Benitez, Jennifer M Loya, Yudilyn Jaramillo, Nancy J Muro-Rodriguez, Oscar F Rojas Perez, Charla Nich, Tami Frankforter, Manuel Paris, Brian D Kiluk

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of substance use and addiction treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Bryan BenitezYale University, School of Medicine, New Haven, CT, United States of America. Electronic address: bryan.benitez@yale.edu.
Jennifer M LoyaYale University, School of Medicine, New Haven, CT, United States of America.
Yudilyn JaramilloYale University, School of Medicine, New Haven, CT, United States of America.
Nancy J Muro-RodriguezUniversity of Georgia, College of Education, Athens, GA, United States of America.
Oscar F Rojas PerezYale University, School of Medicine, New Haven, CT, United States of America.
Charla NichYale University, School of Medicine, New Haven, CT, United States of America.
Tami FrankforterYale University, School of Medicine, New Haven, CT, United States of America.
Manuel ParisYale University, School of Medicine, New Haven, CT, United States of America.
Brian D KilukYale University, School of Medicine, New Haven, CT, United States of America.

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
Research Training Fellowship in Substance use and Addiction (RTFSA)T32DA007238 · NIDA · YALE UNIVERSITY · PI BRIAN D. KILUK, ISMENE L. PETRAKIS · 1988 to 2026
$5.7M
Computer Training in CBT for Spanish-speaking Alcohol UsersR01AA025605 · NIAAA · YALE UNIVERSITY · PI KILUK, BRIAN D., PARIS, MANUEL · 2017 to 2021
$2.6M
Integrating Cognitive Neuroscience Toward Understanding of Mechanisms of CBT for Alcohol Use DisordersK02AA027300 · NIAAA · YALE UNIVERSITY · PI KILUK, BRIAN D. · 2019 to 2023
$719k
Abriendo Caminos: Engaging Latinx Communities Through Culturally Responsive Peer Delivered Motivational InterviewingK23MH130718 · NIMH · YALE UNIVERSITY · PI Oscar Fernando Rojas Perez · 2023 to 2026
$665k
Implementing a Digital Therapeutic to Address Substance Use Disorders among People who Are IncarceratedK23DA061045 · NIDA · YALE UNIVERSITY · PI Jennifer M Loya · 2024 to 2026
$534k
Targeting High Risk Drinking Days with Mobile Treatment for Spanish-Speaking PatientsK99AA031032 · NIAAA · YALE UNIVERSITY · PI BENITEZ, BRYAN · 2023 to 2024
$351k
NCATS NIH HHS UL1 TR001863NIAAA NIH HHS K02 AA027300NIAAA NIH HHS K99 AA031032NIAAA NIH HHS R01 AA025605NIDA NIH HHS K23 DA061045NIDA NIH HHS T32 DA007238NIMH NIH HHS K23 MH130718
6 · The paper itself

Abstract

introductionDeveloping adaptive coping skills for avoiding substance use is a proposed treatment mechanism of cognitive behavioral therapy (CBT) for substance use disorder (SUD). However, the generalizability of research on treatment mechanisms of CBT for SUD is limited by the underrepresentation of racial/ethnic minorities in clinical trials. In a secondary analysis of clinical trial data, we tested whether a culturally-adapted digital CBT program for Hispanics ("Spanish CBT4CBT") improved the quality of coping skills for avoiding substance use. We also tested whether coping skills' quality was associated with reductions in primary substance use.

methodsParticipants were Spanish-speaking Hispanic adults seeking outpatient treatment for SUD (n = 85; 68 % male; primary substance type: 36 % cannabis, 33 % alcohol, 26 % cocaine, 5 % other). They were randomized to 8 weeks of outpatient treatment as usual (TAU) or TAU + Spanish CBT4CBT and assessed for 6 months after treatment. The study conducted separate analyses for the full sample (n = 85) and for those who engaged in at least 5 treatment sessions ("treatment exposed"; n = 64). Daily substance use and coping skills' quality were assessed repeatedly during the treatment and follow-up periods. Bayesian mixed models for repeated measures tested hypotheses.

resultsAmong treatment-exposed participants, those receiving TAU + Spanish CBT4CBT improved the quality of coping skills more than TAU alone during the treatment period (b = 0.77; 95 % CI[0.08, 1.47]), but this difference was not detected during the follow-up period. In the full sample and treatment exposed subsample, participants with higher quality coping skills during the study reported less primary substance use (b = -0.67; 95 % CI[-1.08, -0.26]). Among treatment-exposed participants only, within-person increases in the quality of coping skills were associated with reductions in future primary substance use (b = -0.18; 95 % CI[-0.36, -0.01]).

conclusionsSpanish-speaking Hispanics with SUD may improve the quality of their coping skills more when they are sufficiently exposed to a culturally-adapted digital CBT program during outpatient treatment. Coping skills' quality may be a mechanism of CBT for SUD among Hispanic populations. Spanish-speaking Hispanics' access to treatments that target mechanisms of behavior change may be expanded by digital therapeutics.

Indexed as

Adaptation, PsychologicalCognitive Behavioral TherapyHispanic or LatinoSubstance-Related DisordersAdultCoping SkillsCulturally Competent CareFemaleHumansMaleMiddle AgedCognitive behavioral therapyCoping skillsDigital therapeuticHispanicsSubstance use disorder

Identifiers

PMID39374899
PMCPMC11624081

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.