Evidence map›Paper›PMID 39374538›Full record

ArticleBioinformatics (Oxford, England)2024

BioPred: an R package for biomarkers analysis in precision medicine.

Zihuan Liu, Yan Sun, Xin Huang

Abstract read
In one paragraph

Article in Bioinformatics (Oxford, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zihuan LiuData and Statistical Sciences, AbbVie Inc., North Chicago, IL, 60064, United States.ORCID 0000-0003-4251-1477
Yan SunData and Statistical Sciences, AbbVie Inc., North Chicago, IL, 60064, United States.
Xin HuangData and Statistical Sciences, AbbVie Inc., North Chicago, IL, 60064, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

summaryThe R package BioPred offers a suite of tools for subgroup and biomarker analysis in precision medicine. Leveraging Extreme Gradient Boosting (XGBoost) along with propensity score weighting and A-learning methods, BioPred facilitates the optimization of individualized treatment rules to streamline subgroup identification. BioPred also enables the identification of predictive biomarkers and obtaining their importance rankings. Moreover, the package provides graphical plots tailored for biomarker analysis. This tool enables clinical researchers seeking to enhance their understanding of biomarkers and patient population in drug development. AVAILABILITY AND IMPLEMENTATION: The package is available at CRAN and https://github.com/deeplearner0731/BioPred.

Indexed as

BiomarkersPrecision MedicineSoftwareHumansBiomarkers

Identifiers

PMID39374538
PMCPMC11483108

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.