Article in Proceedings of the National Academy of Sciences of the United States of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
5 · Who and what money
Authors and funding
8 authors.
Wanqi WangDepartment of Neurology, Center for Translational Research in Neurodevelopmental Disease, Columbia University Irving Medical Center, New York, NY 10032.ORCID 0000-0001-7424-9165
Damian J WilliamsDepartment of Neurology, Center for Translational Research in Neurodevelopmental Disease, Columbia University Irving Medical Center, New York, NY 10032.
Jia Jie TeohDepartment of Neurology, Center for Translational Research in Neurodevelopmental Disease, Columbia University Irving Medical Center, New York, NY 10032.
Divyalakshmi SoundararajanDepartment of Neurology, Center for Translational Research in Neurodevelopmental Disease, Columbia University Irving Medical Center, New York, NY 10032.
Aamir ZuberiThe Rare and Orphan Disease Center, The Jackson Laboratory, Bar Harbor, ME 04609.ORCID 0000-0003-0252-9760
Cathleen M LutzThe Rare and Orphan Disease Center, The Jackson Laboratory, Bar Harbor, ME 04609.ORCID 0000-0003-2502-1900
Wayne N FrankelDepartment of Neurology, Center for Translational Research in Neurodevelopmental Disease, Columbia University Irving Medical Center, New York, NY 10032.
Christopher D MakinsonDepartment of Neurology, Center for Translational Research in Neurodevelopmental Disease, Columbia University Irving Medical Center, New York, NY 10032.ORCID 0000-0002-1427-8148
Funding
The Jackson Laboratory Center for Precision GeneticsU54OD030187 · OD · JACKSON LABORATORY · PI Cathleen M Lutz · 2020 to 2026
$17.2M
GENETIC DETERMINANTS OF EPILEPSY IN MURINE SYSTEMSR01NS031348 · NINDS · JACKSON LABORATORY · PI SANDS, TRISTAN T · 1993 to 2025
$11.5M
The Jackson Laboratory Center for Precision Genetics: From New Models to Novel TherapeuticsU54OD020351 · OD · JACKSON LABORATORY · PI LUTZ, CATHLEEN M · 2015 to 2019
$10.2M
Voltage-gated sodium channel regulation of neocortical developmentR00NS104215 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI MAKINSON, CHRISTOPHER DONALD · 2020 to 2022
$744k
TRANSMISSION ELECTRON MICROSCOPES10OD026974 · OD · WEILL MEDICAL COLL OF CORNELL UNIV · PI PICKEL, VIRGINIA M · 2020 to 2020
$543k
Thalamocortical network dysfunction in a novel genetic model of GRIN2D developmental and epileptic encephalopathyR21NS121980 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI FRANKEL, WAYNE N., MAKINSON, CHRISTOPHER DONALD · 2021 to 2021
$446k
American Epilepsy Society (AES) Predoctoral research fellowshipHHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R00-NS104215HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) R01-NS031348HHS | NIH | NIH Office of the Director (OD) U54-OD020351NIH HHS S10 OD026974NIH HHS U54 OD020351NINDS NIH HHS R00 NS104215NINDS NIH HHS R01 NS031348NINDS NIH HHS R21 NS121980
6 · The paper itself
Abstract
Developmental and epileptic encephalopathies (DEE) are rare but devastating and largely intractable childhood epilepsies. Genetic variants in
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Impaired axon initial segment structure and function in a model of · full record | OpenQuestion