Evidence map›Paper›PMID 39374090›Full record

ArticleEuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology2024

Simplification of continuous intracoronary thermodilution.

Thabo Mahendiran, Samer Fawaz, Michele Viscusi, Danielle Keulards, Caïa Crooijmans, Tijn P J Jansen, Henk Everaars, Emanuele Gallinoro, Alessandro Candreva, Frederic Bouisset and 13 more

Abstract read
In one paragraph

Article in EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Invasive Endotyping of Angina Pectoris with Nonobstructive Coronary Arteries.The International journal of angiology : official publication of the International College of Angiology, Inc · 2025
    Review
  3. Coronary flow and resistance patterns indexed by subtended myocardial mass in coronary microvascular dysfunction.EuroIntervention : journal of EuroPCR in collaboration with the Working Group on Interventional Cardiology of the European Society of Cardiology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Thabo MahendiranCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Samer FawazEssex Cardiothoracic Centre, Mid and South Essex NHS Foundation Trust, Basildon, United Kingdom.
Michele ViscusiCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Danielle KeulardsDepartment of Cardiology, Catharina Hospital, Eindhoven, the Netherlands.
Caïa CrooijmansDepartment of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Tijn P J JansenDepartment of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Henk EveraarsDepartment of Cardiology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Emanuele GallinoroCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Alessandro CandrevaDepartment of Cardiology, University Hospital Zurich, Zurich, Switzerland.
Frederic BouissetCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Takuya MizukamiCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Dario BertoloneCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Marta BelmonteCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Ruiko SekiCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Johan SvanerudCoroventis Research, Uppsala, Sweden.
Jeroen SonckCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Adriaan WilgenhofCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Thomas R KeebleEssex Cardiothoracic Centre, Mid and South Essex NHS Foundation Trust, Basildon, United Kingdom.
Peter DammanDepartment of Cardiology, Radboud University Medical Center, Nijmegen, the Netherlands.
Paul KnaapenDepartment of Cardiology, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.
Carlos ColletCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.
Nico H J PijlsDepartment of Cardiology, Catharina Hospital, Eindhoven, the Netherlands.
Bernard De BruyneCardiovascular Center Aalst, OLV Clinic, Aalst, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundContinuous intracoronary thermodilution with saline allows for the accurate measurement of volumetric blood flow (Q) and absolute microvascular resistance (R

aimsWe evaluated whether Ti could be predicted based on known parameters without compromising the accuracy of calculated Q. This would significantly simplify the technique and render it completely operator independent.

methodsIn a derivation cohort of 371 patients with Q measured both at rest and during hyperaemia, multivariate linear regression was used to derive an equation for the prediction of T

resultsSimplified Q exhibited strong agreement with standard Q (r=0.94, confidence interval [CI]: 0.93-0.95; intraclass correlation coefficient [ICC] 0.94, CI: 0.92-0.95; both p<0.001). Simplified Q exhibited excellent agreement with PET-derived Q (r=0.86, CI: 0.75-0.92; ICC=0.84, CI: 0.72-0.91; both p<0.001). Compared with standard Q, there were no statistically significant differences between correlation coefficients (p=0.29) or standard deviations of absolute differences with PET-derived Q (p=0.85).

conclusionsPredicting T

Indexed as

Coronary CirculationThermodilutionAgedCardiac CatheterizationCoronary Artery DiseaseCoronary VesselsFemaleHumansMaleMicrocirculationMiddle AgedReproducibility of ResultsVascular Resistance

Identifiers

PMID39374090
PMCPMC11443253

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.