Evidence map›Paper›PMID 39374074›Full record

ReviewCell transplantation

Hematopoietic Stem Cell Transplantation in the Management of Myelodysplastic Syndrome: A Retrospective, Current, and Future Perspective.

Qimudesiren, Wenjie Yin, Yuhong Wang, Guo Qing, Jinhua Bao, Chaomurilige, Shana Chen, Liren Qian

Abstract readReview
In one paragraph

Review in Cell transplantation. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

QimudesirenSchool of Clinical Medicine, Inner Mongolia Minzu University, Tongliao, China.ORCID 0009-0007-2887-7583
Wenjie YinDepartment of Hematology, International Mongolian Hospital of Inner Mongolia, Hohhot, China.
Yuhong WangDepartment of Hematology, International Mongolian Hospital of Inner Mongolia, Hohhot, China.
Guo QingDepartment of Hematology, International Mongolian Hospital of Inner Mongolia, Hohhot, China.
Jinhua BaoDepartment of Hematology, International Mongolian Hospital of Inner Mongolia, Hohhot, China.
ChaomuriligeDepartment of Hematology, International Mongolian Hospital of Inner Mongolia, Hohhot, China.ORCID 0009-0006-6378-9565
Shana ChenDepartment of Hematology, International Mongolian Hospital of Inner Mongolia, Hohhot, China.
Liren QianSenior Department of Hematology, The Fifth Medical Center of PLA General Hospital, Beijing, China.ORCID 0000-0002-7750-9177

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Myelodysplastic syndrome (MDS) is a clonal disorder that affects hematopoietic stem cells (HSCs), primarily occurring in the elderly population. Lower-risk MDS is characterized by a decrease in blood cells, whereas higher-risk MDS is associated with an increased risk of transformation to acute myeloid leukemia (AML). Currently, the treatment of MDS is still unsatisfactory, although demethylating agents, azacitidine (AZA), and decitabine (Dec) have been successfully used to treat MDS and improve survival rates. However, hematopoietic stem cell transplantation (HSCT) remains the only curative treatment for MDS patients, effectively increasing patient survival and quality of life. Nevertheless, treatment-related toxicity, graft-versus-host disease, infectious complications, and relapse are still major post-transplant issues. In this review, through a retrospective analysis of past and present HSCT for the treatment of MDS, we provide insights for the future.

Indexed as

Hematopoietic Stem Cell TransplantationMyelodysplastic SyndromesHumansRetrospective Studieshematopoietic stem cell transplantationmyelodysplastic syndrome

Identifiers

PMID39374074
PMCPMC11483824

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.