Do Symptoms of Depression Moderate the Links Between Reactive and Proactive Aggression and Frequency of Substance Use?

Youth substance use continues to be a public health concern, with both aggressive behavior and symptoms of depression commonly identified as risk factors for adolescent substance use. However, more research is needed to understand how proactive and reactive functions of aggression are uniquely associated with the frequency of use of specific substances and how these functions of aggression interact with symptoms of depression to contribute to substance use. To this end, the current study examined these associations in a sample of detained youth (N = 229; 80.7% Male). Results suggested that reactive aggression is uniquely associated with traditional cigarette, alcohol, and marijuana use, while proactive aggression is uniquely associated with prescription drug use. Further, although symptoms of depression did not uniquely contribute to the frequency of substance use, symptoms of depression moderate links between proactive aggression and frequency of traditional cigarette, alcohol, and prescription drug use such that proactive aggression is associated with increased frequency of use only when symptoms of depression are low. Findings suggest the need to consider functions of aggression when identifying risk for frequent substance use, as there may be distinct targets of intervention depending on the function of aggression.