Evidence map›Paper›PMID 39373776›Full record

ArticleInternational ophthalmology2024

Is there a relationship between the keratoconus and the peripapillary choroidal vasculature?

Kamran Gahramanov, Metin Unlu, Furkan Ozer, Hidayet Sener, Kuddusi Erkilic

Abstract read
PubMed Publisher
In one paragraph

Article in International ophthalmology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Kamran GahramanovDepartment of Ophthalmology, Division of Cornea, Erciyes University Medical Faculty, Kayseri, Turkey.ORCID https://orcid.org/0000-0001-9487-5446
Metin UnluDepartment of Ophthalmology, Division of Cornea, Erciyes University Medical Faculty, Kayseri, Turkey. drunlumetin@hotmail.com.ORCID https://orcid.org/0000-0003-2505-9853
Furkan OzerDepartment of Ophthalmology, Sungurlu State Hospital, Çorum, Turkey.ORCID https://orcid.org/0000-0002-1384-5868
Hidayet SenerDepartment of Ophthalmology, Division of Cornea, Erciyes University Medical Faculty, Kayseri, Turkey.ORCID https://orcid.org/0000-0001-5836-0170
Kuddusi ErkilicDepartment of Ophthalmology, Division of Cornea, Erciyes University Medical Faculty, Kayseri, Turkey.ORCID https://orcid.org/0000-0002-9216-6301

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo evaluate the peripapillary/parapapillary choroidal vascular parameters in the keratoconus (KC) and to determine the relationship between topography parameters and the peripapillary/parapapillary choroidal vascular parameters.

methodNinety eyes of ninety patients with different stages of KC and 29 eyes of twenty-nine patients without KC were enrolled in the study. Patients with KC were divided into three groups according to the Amsler-Krumeich classification scale. The choroidal vasculature was assessed by choroidal vascular parameters [such as parapapillary choroidal microvascular density (pCMVd) and peripapillary choroidal vascularity index (pCVI)]. These parameters were also evaluated for correlation with other parameters.

resultThe retinal nerve fibre layer thickness (RNFLT) of the superior-temporal area and the pCVI were decreased in group 3 compared to the control group (superiror-temporal RNFLT: 122.27 ± 21.43 vs 139.90 ± 21.7, p = 0.01 and pCVI: 67.04 ± 4.14 vs 69.99 ± 4.38, p = 0.04). The superior-temporal RNFLT was decreased in group 3 compared to group 2 (122.27 ± 21.43 vs 141.83 ± 25.58, p = 0.006). There was a negative correlation between pCVI and average simulated keratometry (mean sim K), but this association was weak (r = - 0.29 p = 0.001).

conclusionThis study demonstrated that there may be changes in pCVI in patients with grade 3 KC and that there may be an association between pCVI and mean sim K. As KC grade increases, pCVI may decrease. Furthermore, pCVI may have a negative correlation with mean sim K.

Indexed as

ChoroidKeratoconusOptic DiskTomography, Optical CoherenceAdolescentAdultCorneal TopographyFemaleHumansMaleNerve FibersRetinal Ganglion CellsVisual AcuityYoung AdultChoroidal vascularity indexKeratoconusParapapillary choroidal microvascular densityRetinal nerve fiber layer thickness

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.