Evidence map›Paper›PMID 39373765›Full record

SynthesisArchives of orthopaedic and trauma surgery2024

Different peripheral nerve blocks for patients undergoing total knee arthroplasty: a network meta-analysis of randomized controlled trials.

Faxing Wang, Jimin Wu, Yini Wu, Xin Han, Hong Dai, Qin Chen

Abstract readSystematic ReviewNetwork Meta-Analysis
PubMed Full text at PMC Publisher
In one paragraph

Synthesis in Archives of orthopaedic and trauma surgery, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Faxing Wang *Department of Anesthesiology, Lishui People's Hospital, Lishui Hospital of Wenzhou Medical University, No. 1188 Liyang Street, Lishui, Zhejiang, 323000, People's Republic of China.
Jimin Wu *Department of Anesthesiology, Lishui People's Hospital, Lishui Hospital of Wenzhou Medical University, No. 1188 Liyang Street, Lishui, Zhejiang, 323000, People's Republic of China.
Yini WuDepartment of Anesthesiology, Lishui People's Hospital, Lishui Hospital of Wenzhou Medical University, No. 1188 Liyang Street, Lishui, Zhejiang, 323000, People's Republic of China.
Xin HanDepartment of Anesthesiology, Lishui People's Hospital, Lishui Hospital of Wenzhou Medical University, No. 1188 Liyang Street, Lishui, Zhejiang, 323000, People's Republic of China.
Hong DaiDepartment of Anesthesiology, Lishui People's Hospital, Lishui Hospital of Wenzhou Medical University, No. 1188 Liyang Street, Lishui, Zhejiang, 323000, People's Republic of China.
Qin ChenDepartment of Anesthesiology, Lishui People's Hospital, Lishui Hospital of Wenzhou Medical University, No. 1188 Liyang Street, Lishui, Zhejiang, 323000, People's Republic of China. qinchen_ls@163.com.

Funding

the Zhejiang Provincial Medical and Health Science and Technology Plan Project 2022ZH095the Zhejiang Provincial Medical and Health Science and Technology Plan Project 2022ZH098the Zhejiang Provincial Medical and Health Science and Technology Plan Project 2023KY1378the Zhejiang Provincial Medical and Health Science and Technology Plan Project 2024XY230the Zhejiang Provincial Medical Association Clinical Research Fund Project 2018ZYC-A163
6 · The paper itself

Abstract

introductionTo comprehensively compare the effect of different peripheral nerve blocks for patients undergoing total knee arthroplasty (TKA). MATERIALS AND

methodsPubMed, Embase, Cochrane Library, and Web of Science were comprehensively searched. The outcomes included postoperative pain, postoperative function, adverse events, oral morphine equivalent (OME), and perioperative indicators. Network plots, forest plots, league tables and rank probabilities were drawn for all outcomes.

resultsTotally 30 studies were included. For postoperative pain, continuous adductor canal block (cACB) + genicular nerve block (GNB) was most likely to be the most effective block regarding rest pain score at 24 h; cACB + GNB was most likely to result in the lowest rest pain score at 48 h; patients undergoing cACB + infiltration between the popliteal artery and the capsule of the knee (IPACK) + GNB was most likely to have the lowest motion pain score at 24 h; patients undergoing cACB + GNB was most likely to have the lowest motion pain score at 48 h. For postoperative function, patients undergoing cACB + IPACK + GNB had the highest likelihood to exhibit the shortest time in Timed Up and Go test (TUG); cACB + tibial nerve block (TNB) was most likely to be the most effective block in terms of range of motion (ROM); cACB + IPACK was most likely to be the optimal block concerning the ambulation distance.

conclusioncACB combined with IPACK/GNB may be the most favorable block after TKA, continuous blocks may be better than single-shot blocks, and combined blocks may be better than separate blocks.

Indexed as

Arthroplasty, Replacement, KneeNerve BlockPostoperative PainRandomized Controlled Trials as TopicHumansPeripheral NervesNetwork meta-analysisPeripheral nerve blockRandomized controlled trialTotal knee arthroplasty

Identifiers

PMID39373765
PMCPMC11564395

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.