Evidence map›Paper›PMID 39373647›Full record

ArticleJournal of sex research2025

The Impact of Pleasure and Pain on Frequent Substance Use During Receptive Anal Intercourse.

Tara Shahrvini, Thomas W Gaither, Nathan W Vincent, Kristen C Williams, Eduardo Piqueiras, Allen E Siapno, Marcia M Russell, Mark S Litwin

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of sex research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tara ShahrviniDavid Geffen School of Medicine, University of California Los Angeles.ORCID 0000-0003-2178-170X
Thomas W GaitherDepartment of Urology, David Geffen School of Medicine, University of California Los Angeles.
Nathan W VincentIndependent Researcher.
Kristen C WilliamsDepartment of Urology, David Geffen School of Medicine, University of California Los Angeles.
Eduardo PiqueirasDepartment of Urology, David Geffen School of Medicine, University of California Los Angeles.ORCID 0000-0002-7822-3971
Allen E SiapnoDepartment of Urology, David Geffen School of Medicine, University of California Los Angeles.
Marcia M RussellDepartment of Surgery, Section of Colorectal Surgery, David Geffen School of Medicine, University of California Los Angeles.
Mark S LitwinDepartment of Urology, David Geffen School of Medicine, University of California Los Angeles.

Funding

Patient-Centered Outcomes Research Training in Urologic and Gynecologic Cancers (PCORT UroGynCan)T32CA251072 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Beth Y. Karlan, MARK S. LITWIN · 2020 to 2026
$2.1M
NCI NIH HHS T32 CA251072
6 · The paper itself

Abstract

Sexualized drug use (SDU) describes use of any psychoactive substance before or during planned sexual activity to facilitate, intensify, or prolong intercourse. The impact of pain, pleasure, and other mediators on SDU is not well characterized. This study aimed to distinguish the motivations behind different classes and frequencies of substance use during receptive anal intercourse (RAI). Data were from an internet-based survey conducted between July 2022-January 2023. We measured the frequency of SDU for five substances: poppers, alcohol, marijuana, methamphetamine, and nicotine. Satisfaction with pleasurable sensations during RAI and any type of pain bother during RAI were assessed on a 5-point scale. Multivariable logistic regression was performed for 1,119 respondents. Our results showed a strong association between bothersome pain during RAI and frequent alcohol (aOR 2.1), marijuana (aOR 2.4), nicotine (aOR 3.1), and meth (aOR 5.9) use. None of the five substance classes studied was correlated with dissatisfaction with pleasure during RAI. Frequent popper use was associated with increasing lifetime RAI experience and number of sexual partners. The mechanism behind SDU during RAI is substance-specific and multifactorial. Bothersome pain during RAI is highly associated with frequent SDU. Inquiring about pain during RAI may offer avenues for intervention.

Indexed as

PainPleasureSexual BehaviorSubstance-Related DisordersAdolescentAdultFemaleHumansMaleMiddle AgedYoung Adult

Identifiers

PMID39373647
PMCPMC12802364

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.