Evidence map›Paper›PMID 39373160›Full record

ArticleFuture medicinal chemistry2024

A long march for targeted protein degradation in the new era: expanding E3 ligases.

Dazhao Mi, Anxin Huang, Jingfeng Song, Yihua Chen

Abstract readEditorial
In one paragraph

Article in Future medicinal chemistry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Dazhao MiShanghai Key Laboratory of Regulatory Biology, The Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai, 200241, China.ORCID 0000-0002-1385-8917
Anxin HuangShanghai Key Laboratory of Regulatory Biology, The Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai, 200241, China.ORCID 0009-0005-3961-1241
Jingfeng SongSchool of Pharmaceutical Sciences and Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Kunming, Yunnan, 650500, China.ORCID 0009-0007-7615-7660
Yihua ChenShanghai Key Laboratory of Regulatory Biology, The Institute of Biomedical Sciences, School of Life Sciences, East China Normal University, Shanghai, 200241, China.ORCID 0000-0003-1733-7980

Funding

CPSF GZC20240483The Open Fund Project of Yunnan Key Laboratory of Pharmacology for Natural Products YKLPNP-G2402The Science Research Foundation of Yunnan Provincial Education Department 2024J0148Yunnan Applied Basic Research-Joint Special Project of Kunming Medical University 202401AY070001-0325
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

E3 ligasesmolecular gluesPROTACstargeted protein degradationundruggable therapeutic targets

Identifiers

PMID39373160
PMCPMC11622777

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.