Evidence map›Paper›PMID 39373020›Full record

SynthesisHuman vaccines & immunotherapeutics2024

Inequalities in the risk and prevention of invasive meningococcal disease in the United States - A systematic literature review.

Shahina Begum, Oscar Herrera-Restrepo, Catherine Rolland, Sneha Purushotham, Anar Andani, Hiral Shah, Zeki Kocaata

Abstract readSystematic Review
In one paragraph

Synthesis in Human vaccines & immunotherapeutics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Observational
  6. Article
  7. Review
  8. Review
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Shahina BegumGSK, London, UK.ORCID 0000-0002-3521-8865
Oscar Herrera-RestrepoGSK, Philadelphia, PA, USA.ORCID 0000-0001-8193-999X
Catherine RollandEvidera, The Ark, London, UK.
Sneha PurushothamEvidera, The Ark, London, UK.
Anar AndaniGSK, London, UK.
Hiral ShahGSK, London, UK.ORCID 0000-0003-0204-451X
Zeki KocaataGSK, Wavre, Belgium.ORCID 0000-0002-5231-3389

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Vaccination remains the most effective strategy to prevent invasive meningococcal disease (IMD), with MenACWY, MenB and MenABCWY recommended for adolescents/young adults in the United States (US). However, vaccination coverage remains suboptimal, which could be related to population inequalities. To understand the impact of IMD risk, prevention and control inequalities, a global systematic literature review (Medline, Embase, 2012-2022) was conducted on individual, socioeconomic, and environmental inequalities associated with IMD risk, prevention and control in all ages. Studies on IMD risk (n = 15) and prevention (n = 14) inequalities were identified. IMD incidence proportions were higher in Medicaid versus commercially insured populations, and IMD mortality was higher in poorer neighborhoods. White adolescents, adolescents from lower income families, and with lower maternal education were more likely to receive MenB vaccination; while Black and Hispanic adolescents, and adolescents with higher family incomes, were more likely to receive MenACWY vaccination. Meningococcal vaccination was associated with being up-to-date with other vaccinations, having multiple healthcare/well child visits, having a pediatrician as healthcare provider (HCP), and attending private facilities; while being uninsured was associated with lower vaccination. States with a MenACWY vaccination mandate and higher pediatrician-to-children ratios had higher vaccination rates. Important inequalities were due to individual differences, socioeconomic, and environmental factors. IMD prevention is suboptimal, especially among adolescents/young adults. To improve health equity, health policy makers could ameliorate meningococcal vaccination coverage across the US, with simplified and stronger meningococcal vaccine recommendations from public health authorities, and initiatives to enhance parental/patient and HCP knowledge of IMD and vaccine recommendations.

Indexed as

Meningococcal InfectionsMeningococcal VaccinesAdolescentHealthcare DisparitiesHumansNeisseria meningitidisSocioeconomic FactorsUnited StatesVaccinationVaccination CoverageYoung AdultMeningococcal Vaccinesbacterial meningitishealth equityinequalityInvasive meningococcal diseasepreventionUnited States

Identifiers

PMID39373020
PMCPMC11459729

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.