Evidence map›Paper›PMID 39373000›Full record

ArticleSurgical neurology international2024

3D ultrasound-augmented image guidance for surgery of high-grade gliomas - A quantitative analysis focused on the extent of resection.

Giulio Anichini, Islam Shah, Dominic Edward Mahoney, Neekhil Patel, Lillie Pakzad-Shahabi, Olga Fadeeva Da Costa, Nelofer Syed, Richard Perryman, Adam Waldman, Kevin O'Neill

Abstract read
In one paragraph

Article in Surgical neurology international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Giulio AnichiniDepartment of Brain Sciences, Imperial College London, England, United Kingdom.
Islam ShahDepartment of Surgery and Cancer, Neuroradiology, Imperial College London, England, United Kingdom.
Dominic Edward MahoneyDepartment of Neurosurgery, Queens Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, England, United Kingdom.
Neekhil PatelDepartment of Brain Sciences, Imperial College London, England, United Kingdom.
Lillie Pakzad-ShahabiDepartment of Neuro-oncology, Imperial College of London, London, England, United Kingdom.
Olga Fadeeva Da CostaDepartment of Imaging, Imperial College of London, London, England, United Kingdom.
Nelofer SyedDepartment of Brain Sciences, Imperial College London, England, United Kingdom.
Richard PerrymanDepartment of Brain Sciences, Imperial College London, England, United Kingdom.
Adam WaldmanCentre for Clinical Brain Science, University of Edinburgh, Edinburgh, Scotland, United Kingdom.
Kevin O'NeillDepartment of Brain Sciences, Imperial College London, England, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We have retrospectively reviewed our series of brain tumor patients operated on using 3D IntraOperative UltraSound (IOUS) to report technical advantages and areas of improvement. Methods: Clinical and radiological data of patients with a diagnosis of high-grade glioma IV operated with and without IOUS were retrieved and analyzed. Results: We have found 391 patients operated using IOUS coupled with neuronavigation and 257 using neuronavigation standalone. We have selected a pool of 60 patients with a diagnosis of GlioBlastoma (GB), comparing two equally sized groups operated with and without IOUS, respectively. The average extent of resection (EOR) in the IOUS group was 93%, while in the control group, it was 80%. IOUS was significantly associated with improved EOR ( Conclusion: Intraoperative ultrasound coupled with image guidance is associated with an improved EOR and possibly an improved OS. While we are aware of several limitations related to the present analysis, these data support the routine use of IOUS as a safe and reliable technology. Larger, prospective series with updated IOUS technology are desirable to verify the accuracy of these results.

Indexed as

3D ultrasoundHigh-grade gliomaIntraoperative ultrasoundNeuro-oncologyUltrasound

Identifiers

PMID39373000
PMCPMC11450865

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.