Evidence map›Paper›PMID 39372939›Full record

ArticleResearch square2024

Stochasticity in Dietary Restriction-Mediated Lifespan Outcomes in

Olivia L Mosley, Joel A Villa, Advaitha Kamalakkannan, Eliyashaib James, Jessica M Hoffman, Yang Lyu

Abstract readPreprint
In one paragraph

Article in Research square, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Olivia L MosleyDepartment of Biological Sciences, Augusta University, Augusta, GA, USA.
Joel A VillaDepartment of Molecular Biology and Biochemistry, Rutgers, the State University of New Jersey, New Brunswick, NJ, USA.
Advaitha KamalakkannanDepartment of Molecular Biology and Biochemistry, Rutgers, the State University of New Jersey, New Brunswick, NJ, USA.
Eliyashaib JamesDepartment of Molecular Biology and Biochemistry, Rutgers, the State University of New Jersey, New Brunswick, NJ, USA.
Jessica M HoffmanDepartment of Biological Sciences, Augusta University, Augusta, GA, USA.
Yang LyuDepartment of Molecular Biology and Biochemistry, Rutgers, the State University of New Jersey, New Brunswick, NJ, USA.ORCID https://orcid.org/0000-0002-4618-9043

Funding

The metabolomic consequences of small size and long lifeR00AG059920 · NIA · AUGUSTA UNIVERSITY · PI HOFFMAN, JESSICA MARIE · 2022 to 2024
$742k
NIA NIH HHS R00 AG059920
6 · The paper itself

Abstract

Dietary restriction (DR) is widely considered to be one of the most potent approaches to extend healthy lifespan across various species, yet it has become increasingly apparent that DR-mediated longevity is influenced by biological and non-biological factors. We propose that current priorities in the field should include understanding the relative contributions of these factors to elucidate the mechanisms underlying the beneficial effects of DR. Our work conducted in two laboratories, represents an attempt to unify DR protocols in

Identifiers

PMID39372939
PMCPMC11451724

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.