Evidence map›Paper›PMID 39372838›Full record

ArticlePain research & management2024

Blockade of Piezo2 Pathway Attenuates Inflammatory and Neuropathic Pain in the Orofacial Area.

Min-Jeong Jo, Jo-Young Son, Yu-Mi Kim, Jin-Sook Ju, Min-Kyoung Park, Min-Kyung Lee, Dong-Kuk Ahn

Abstract read
In one paragraph

Article in Pain research & management, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Min-Jeong JoDepartment of Oral Physiology School of Dentistry Kyungpook National University, Daegu, Republic of Korea.
Jo-Young SonDepartment of Oral Physiology School of Dentistry Kyungpook National University, Daegu, Republic of Korea.
Yu-Mi KimDepartment of Oral Physiology School of Dentistry Kyungpook National University, Daegu, Republic of Korea.
Jin-Sook JuDepartment of Oral Physiology School of Dentistry Kyungpook National University, Daegu, Republic of Korea.
Min-Kyoung ParkDepartment of Dental Hygiene Kyung-Woon University, Gumi, Republic of Korea.
Min-Kyung LeeDepartment of Dental Hygiene Dong-Eui University, Busan, Republic of Korea.
Dong-Kuk AhnDepartment of Oral Physiology School of Dentistry Kyungpook National University, Daegu, Republic of Korea.ORCID 0000-0002-5570-2371

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although previous studies suggest that Piezo2 regulates chronic pain in the orofacial area, few studies have reported the direct evidence of Piezo2's involvement in inflammatory and neuropathic pain in the orofacial region. In this study, we used male Sprague Dawley rats to investigate the role of the Piezo2 pathway in the development of inflammatory and neuropathic pain. The present study used interleukin (IL)-1

Indexed as

Facial PainHyperalgesiaNeuralgiaRats, Sprague-DawleyAnimalsDisease Models, AnimalInflammationInterleukin-1betaIon ChannelsMaleRatsSignal TransductionTrigeminal GanglionInterleukin-1betaIon Channelspiezo2 protein, ratacute painantinociceptioninterleukin-1βneuropathic painPiezo2

Identifiers

PMID39372838
PMCPMC11452243

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.