Evidence map›Paper›PMID 39372779›Full record

ArticlebioRxiv : the preprint server for biology2025

Programmed ribosomal frameshifting during

Gary Loughran, Raffaella De Pace, Ningyu Ding, Jianchao Zhang, Irwin Jungreis, Gionmattia Carancini, Jonathan M Mudge, Ji Wang, Manolis Kellis, John F Atkins and 5 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Gary LoughranSchool of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.
Raffaella De PaceNeurosciences and Cellular and Structural Biology Division, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Ningyu DingDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, Republic of China and Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China.
Jianchao ZhangDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, Republic of China and Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China.
Irwin JungreisMIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA.
Gionmattia CaranciniSchool of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.
Jonathan M MudgeEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Hinxton CB10 1SD, Cambridge, UK.
Ji WangDepartment of Pathology, University of Cambridge, Cambridge, UK.
Manolis KellisMIT Computer Science and Artificial Intelligence Laboratory, Cambridge, MA, USA.ORCID 0000-0001-7113-9630
John F AtkinsSchool of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.
Pavel V BaranovSchool of Biochemistry and Cell Biology, University College Cork, Cork, Ireland.
Andrew E FirthDepartment of Pathology, University of Cambridge, Cambridge, UK.
Xiaowei LiDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, Henan, Republic of China and Henan Key Laboratory of Hereditary Cardiovascular Diseases, Zhengzhou 450052, China.
Juan S BonifacinoNeurosciences and Cellular and Structural Biology Division, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892, USA.
Yousuf A KhanDepartment of Molecular and Cellular Physiology, Stanford University, Stanford, CA, USA.ORCID 0000-0003-0201-2796

Funding

GENCODE Resource ProjectU41HG007234 · NHGRI · SANGER INSTITUTE · PI FLICEK, PAUL · 2013 to 2020
$20.3M
GENCODE: comprehensive reference genome annotation for human and mouseU24HG007234 · NHGRI · EUROPEAN MOLECULAR BIOLOGY LABORATORY · PI Fergal James Martin · 2021 to 2026
$16.1M
REGULATION OF THE FATE OF NEWLY SYNTHESIZED PROTEINSZ01HD001607 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BONIFACINO, JUAN · 1991 to 2008
$4.4M
Regulatory Morif Discovery in the Human Genome Using Comparative GenomicsR01HG004037 · NHGRI · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI KELLIS, MANOLIS · 2007 to 2015
$3.9M
Mechanistic Principles of SNARE Disassembly in Neurotransmitter ReleaseF31MH134477 · NIMH · STANFORD UNIVERSITY · PI KHAN, YOUSUF A · 2023 to 2025
$84k
Intramural NIH HHS Z01 HD001607NHGRI NIH HHS R01 HG004037NHGRI NIH HHS U24 HG007234NHGRI NIH HHS U41 HG007234NIMH NIH HHS F31 MH134477Wellcome Trust
6 · The paper itself

Abstract

Programmed ribosomal frameshifting is a process where a proportion of ribosomes change their reading frame on an mRNA

Identifiers

PMID39372779
PMCPMC11451614

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.