Evidence map›Paper›PMID 39372750›Full record

ArticlebioRxiv : the preprint server for biology2024

MLL4 regulates postnatal palate growth and midpalatal suture development.

Jung-Mi Lee, Hunmin Jung, Bruno de Paula Machado Pasqua, Yungki Park, Qinghuang Tang, Shin Jeon, Soo-Kyung Lee, Jae W Lee, Hyuk-Jae Edward Kwon

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

9 authors.

Jung-Mi LeeDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, NY 14214, U.S.A.ORCID 0000-0003-1231-582X
Hunmin JungDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, NY 14214, U.S.A.
Bruno de Paula Machado PasquaDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, NY 14214, U.S.A.
Yungki ParkDepartment of Biochemistry, Jacobs School of Medicine and Biomedical Sciences, Institute for Myelin and Glia Exploration, University at Buffalo, The State University of New York, Buffalo, NY 14203, U.S.A.ORCID 0000-0003-2839-848X
Qinghuang TangDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, NY 14214, U.S.A.ORCID 0000-0002-9436-8628
Shin JeonDepartment of Biological Sciences, College of Arts and Sciences, FOXG1 Research Center, University at Buffalo, The State University of New York, Buffalo, NY 14260, U.S.A.
Soo-Kyung LeeDepartment of Systems Pharmacology & Translational Therapeutics, Institute for Immunology, University of Pennsylvania, PA 19104, U.S.A.ORCID 0000-0002-1745-256X
Jae W LeeDepartment of Systems Pharmacology & Translational Therapeutics, Institute for Immunology, University of Pennsylvania, PA 19104, U.S.A.ORCID 0000-0001-7439-643X
Hyuk-Jae Edward KwonDepartment of Oral Biology, School of Dental Medicine, University at Buffalo, The State University of New York, Buffalo, NY 14214, U.S.A.ORCID 0000-0001-6538-6045

Funding

University of Buffalo Clinical and Translational Science Institute - Supplement SchulyerUL1TR001412 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI MURPHY, TIMOTHY F · 2015 to 2024
$33.8M
Institutional Career DevelopmentKL2TR001413 · NCATS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI DUBOCOVICH, MARGARITA L · 2015 to 2024
$4.2M
Advanced Training in Oral BiologyT32DE023526 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Stefan Hans-Klaus Ruhl · 2013 to 2026
$3.7M
Genomic and functional investigations of the transcriptional regulatory network of tooth enamel developmentR01DE033085 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI Hyuk Jae Edward Kwon · 2023 to 2026
$2.5M
FoxG1-directed Gene Network in Forebrain Development and FoxG1 SyndromeR01NS100471 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI LEE, SOO-KYUNG · 2017 to 2021
$2.4M
Transcription Factors Governing the Development of GHRH-neuronsR01NS118748 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI LEE, JAE W, LEE, SOO-KYUNG · 2021 to 2024
$2.2M
Transcriptional Regulators of Motor Columnar SpecificationR01NS111760 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI LEE, SOO-KYUNG · 2019 to 2023
$2.0M
Role of Pacs2 in central nervous system myelinationR21NS123775 · NINDS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI PARK, YUNGKI · 2021 to 2021
$439k
Epigenetic regulatory roles of Mll4 in palate developmentR03DE030985 · NIDCR · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI KWON, HYUK JAE EDWARD · 2021 to 2022
$319k
NCATS NIH HHS KL2 TR001413NCATS NIH HHS UL1 TR001412NIDCR NIH HHS R01 DE033085NIDCR NIH HHS R03 DE030985NIDCR NIH HHS T32 DE023526NINDS NIH HHS R01 NS100471NINDS NIH HHS R01 NS111760NINDS NIH HHS R01 NS118748NINDS NIH HHS R21 NS123775
6 · The paper itself

Abstract

MLL4, also known as KMT2D, is a histone methyltransferase that acts as an important epigenetic regulator in various organogenesis programs. Mutations in the

Identifiers

PMID39372750
PMCPMC11451598

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.