Evidence map›Paper›PMID 39372611›Full record

ArticleIndian journal of nephrology

Prevalence of Chronic Kidney Disease and its Association with Pesticide Exposure in Bargarh District, Odisha, India.

Pralaya Biswas, Ashish Kumar Sahu, Soumya Ranjan Nath, Showkat Ahmad Mir, Pradeep Kumar Naik, Ekamber Kariali, Binata Nayak, Sourav Shristi, Satish Kumar Nayak, Iswar Baitharu

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Article in Indian journal of nephrology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

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  6. 2024 - A Year in Review.Indian journal of nephrology
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Pralaya BiswasToxicopathology Laboratory, Department of Environmental Sciences, Sambalpur University, Odisha, India.
Ashish Kumar SahuToxicopathology Laboratory, Department of Environmental Sciences, Sambalpur University, Odisha, India.
Soumya Ranjan NathToxicopathology Laboratory, Department of Environmental Sciences, Sambalpur University, Odisha, India.
Showkat Ahmad MirSchool of Life Sciences, Sambalpur University, Odisha, India.
Pradeep Kumar NaikDepartment of Biotechnology and Bioinformatics, Sambalpur University, Odisha, India.
Ekamber KarialiSchool of Life Sciences, Sambalpur University, Odisha, India.
Binata NayakSchool of Life Sciences, Sambalpur University, Odisha, India.
Sourav ShristiDepartment of Nephrology, Veer Surendra Sai Institute of Medical Science and Research, Odisha, India.
Satish Kumar NayakPublic Health (Epidemiology) Section, District Headquarter Hospital, Bargarh, Odisha, India.
Iswar BaitharuToxicopathology Laboratory, Department of Environmental Sciences, Sambalpur University, Odisha, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bargarh, a district in Odisha, is known for intense agricultural activities because of uninterrupted irrigation from the Hirakud reservoir. The number of chronic kidney disease (CKD) cases in the district is increasing rapidly. The present study assesses the prevalence of CKD and CKDu (of unknown etiology) in the district and its association with pesticide application. Materials and Methods: A door-to-door survey was conducted to find out the CKD hotspots in the different blocks of the district with the help of primary and community health centers. The prevalence of CKD in the identified hotspot villages was assessed using a random clustered sampling method along with the collection of data related to age, sex, occupation and source of drinking water. Soil and water samples collected from identified hotspot and nonhotspot villages were analyzed to assess the presence of nephrotoxic pesticide residues. Results: A total of 16 villages were identified with high CKD prevalence rates and designated as hotspot villages. Data indicate that about 21% of males under ≥ 40 years age group were found to be suffering from CKD. Cases of CKDu (85%) were more prominent in these hotspot villages. Analysis of soil and water samples demonstrated the presence of seven different nephrotoxic pesticides above the maximum residues levels (MRLs) in hotspot villages compared to nonhotspot villages. Conclusion: The presence of nephrotoxic pesticides above MRLs in the hotspot villages indicates their possible association with the onset and progression of CKD among the exposed population. Further research is needed to establish their causative association with CKDu in the study region.

Indexed as

Bargarh districtCKD PrevalenceCommunity based surveyOdishaPesticide

Identifiers

PMID39372611
PMCPMC11450900

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.