Evidence map›Paper›PMID 39372421›Full record

ReviewFrontiers in immunology2024

The negative effects of extracellular vesicles in the immune system.

Yang Wang, Cuifang Li, Feifeng Wu, Jueyi Mao, Junquan Zhu, Haotian Xie, Xin Zhou, Chuan Wen, Jidong Tian

Abstract readReview
In one paragraph

Review in Frontiers in immunology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Review
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Yang WangDepartment of Pediatrics, The Second Xiangya Hospital of Central South University, Changsha, China.
Cuifang LiDepartment of Pediatrics, The Second Xiangya Hospital of Central South University, Changsha, China.
Feifeng WuDepartment of Pediatrics, The Second Xiangya Hospital of Central South University, Changsha, China.
Jueyi MaoDepartment of Pediatrics, The Second Xiangya Hospital of Central South University, Changsha, China.
Junquan ZhuDepartment of Pediatrics, The Second Xiangya Hospital of Central South University, Changsha, China.
Haotian XieDepartment of Pediatrics, The Second Xiangya Hospital of Central South University, Changsha, China.
Xin ZhouDepartment of Pediatrics, The Second Xiangya Hospital of Central South University, Changsha, China.
Chuan WenDepartment of Pediatrics, The Second Xiangya Hospital of Central South University, Changsha, China.
Jidong TianDepartment of Gastroenterology, The Second Xiangya Hospital of Central South University, Changsha, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Immunity is a critical self-defense mechanism of the human body, wherein immune cells and immune molecules play a crucial role. Extracellular vesicles (EVs), derived from immune cells or other cells, play a significant role in tumors, autoimmune diseases and other immune-related disorders by serving as carriers and facilitating intercellular communication through the transfer of cargoes. Numerous studies have revealed that EVs can exacerbate disease development by modulating immune responses. Therefore, this paper focuses on the effects of EVs on the number, activity and function of different types of immune cells and the release of immune molecules (such as cytokines, antigens, antibodies, etc) in various diseases, as well as the roles of EVs associated with different types of immune cells in various diseases. We aim to provide a comprehensive review of the negative effects that EVs play in the immune system to provide more ideas and strategies for the management of clinical immune diseases.

Indexed as

Extracellular VesiclesImmune SystemAnimalsAutoimmune DiseasesCell CommunicationHumansNeoplasmsB cellextracellular vesiclesimmunemacrophagemonocyteneutrophilT cell

Identifiers

PMID39372421
PMCPMC11449741

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.