Evidence map›Paper›PMID 39372265›Full record

ArticleJournal of open source software2023

SMITE: Single Molecule Imaging Toolbox Extraordinaire (MATLAB).

David J Schodt, Michael J Wester, Mohamadreza Fazel, Sajjad Khan, Hanieh Mazloom-Farsibaf, Sandeep Pallikkuth, Marjolein B M Meddens, Farzin Farzam, Eric A Burns, William K Kanagy and 7 more

Abstract read
In one paragraph

Article in Journal of open source software, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
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  4. Review
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  6. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

David J SchodtDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, United States of America.ORCID 0000-0002-8986-2736
Michael J WesterDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, United States of America.ORCID 0000-0002-3520-7605
Mohamadreza FazelDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, United States of America.ORCID 0000-0002-6215-1336
Sajjad KhanDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, United States of America.ORCID 0000-0002-6910-5199
Hanieh Mazloom-FarsibafDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, United States of America.ORCID 0000-0002-2571-0418
Sandeep PallikkuthDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, United States of America.ORCID 0009-0003-0400-6389
Marjolein B M MeddensDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, United States of America.ORCID 0000-0002-9965-1342
Farzin FarzamDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, United States of America.ORCID 0000-0002-9939-1923
Eric A BurnsDepartment of Pathology, University of New Mexico Health Sciences Center, Albuquerque, United States of America.ORCID 0000-0002-1625-2400
William K KanagyDepartment of Pathology, University of New Mexico Health Sciences Center, Albuquerque, United States of America.ORCID 0000-0002-5756-9965
Derek A RinaldiDepartment of Pathology, University of New Mexico Health Sciences Center, Albuquerque, United States of America.ORCID 0009-0000-8394-3626
Elton JhambaDepartment of Pathology, University of New Mexico Health Sciences Center, Albuquerque, United States of America.ORCID 0000-0002-5272-6466
Sheng LiuDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, United States of America.ORCID 0000-0003-1225-0763
Peter K RelichDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, United States of America.ORCID 0000-0002-6063-6233
Mark J OlahDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, United States of America.
Stanly L SteinbergDepartment of Mathematics and Statistics, Albuquerque, University of New Mexico, United States of America.
Keith A LidkeDepartment of Physics and Astronomy, University of New Mexico, Albuquerque, United States of America.ORCID 0000-0002-9328-4318

Funding

WOMEN'S CANCERS RESEARCH PROGRAMP30CA118100 · NCI · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Yolanda Sanchez · 2005 to 2026
$57.1M
UNM TRAININGP50GM085273 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI LIDKE, KEITH A · 2009 to 2018
$26.1M
FAIR Data Competency and Machine Learning Readiness for Biomedical ScientistsK12GM088021 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI REBECCA S. HARTLEY, Diane Lidke · 2009 to 2026
$16.4M
TRAINING GRANT IN MICROBIOLOGY/CANCER RESEARCHT32CA009138 · NCI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Scott M. Dehm · 1985 to 2026
$11.3M
Imaging the Early Events in Membrane Receptor SignalingR35GM126934 · NIGMS · UNIVERSITY OF NEW MEXICO HEALTH SCIS CTR · PI Diane Lidke · 2018 to 2026
$3.1M
Understanding how receptor tyrosine kinase activation dynamics specify proliferative cellular responsesR01CA248166 · NCI · YALE UNIVERSITY · PI LEMMON, MARK A, LIDKE, DIANE · 2020 to 2024
$2.6M
Adaptive Tracking and Quantum Imaging for Protein-Protein InteractionsR01GM140284 · NIGMS · UNIVERSITY OF NEW MEXICO · PI BECERRA CHAVEZ, FRANCISCO ELOHIM, LIDKE, KEITH A · 2022 to 2025
$1.8M
Structural and Functional Interactions within the Neuronal ER/PM JunctionR01GM109888 · NIGMS · COLORADO STATE UNIVERSITY · PI BEAM, KURT G, KRAFT, MARY L · 2014 to 2017
$1.5M
Reflected Beam Illumination Microscopy using a Microfluidics DeviceR21GM104691 · NIGMS · UNIVERSITY OF NEW MEXICO · PI LIDKE, KEITH A · 2012 to 2014
$598k
A hyperspectral microscope optimized for spectrally multiplexed live cell imagingR21RR024438 · NCRR · UNIVERSITY OF NEW MEXICO · PI LIDKE, KEITH A · 2009 to 2011
$520k
Measuring Protein-Protein Interactions using SPT-RESOLFTR21GM132716 · NIGMS · UNIVERSITY OF NEW MEXICO · PI LIDKE, KEITH A · 2019 to 2020
$393k
Multi-target super-resolution imaging using sequential labelingR21EB019589 · NIBIB · UNIVERSITY OF NEW MEXICO · PI LIDKE, KEITH A · 2015 to 2016
$390k
NCI NIH HHS P30 CA118100NCI NIH HHS R01 CA248166NCI NIH HHS T32 CA009138NCRR NIH HHS R21 RR024438NIBIB NIH HHS R21 EB019589NIGMS NIH HHS K12 GM088021NIGMS NIH HHS P50 GM085273NIGMS NIH HHS R01 GM109888NIGMS NIH HHS R01 GM140284NIGMS NIH HHS R21 GM104691NIGMS NIH HHS R21 GM132716NIGMS NIH HHS R35 GM126934
6 · The paper itself

Abstract

Fluorescence single molecule imaging comprises a variety of techniques that involve detecting individual fluorescent molecules. Many of these techniques involve localizing individual fluorescent molecules with precisions below the diffraction limit, which limits the spatial resolution of (visible) light-based microscopes. These methodologies are widely used to image biological structures at the nanometer scale by fluorescently tagging the structures of interest, elucidating details of the biological behavior observed. Two common techniques are single-molecule localization microscopy (SMLM), (Betzig et al., 2006; Fazel & Wester, 2022; Hell, 2007; Lidke et al., 2005; Rust et al., 2006; van de Linde et al., 2011) which is used to produce 2D or 3D super-resolution images of static or nearly static structures, and single-particle tracking (SPT) (Shen et al., 2017), which follows the time course of one or a very small number of moving tagged molecules. SMLM often involves distributions of particles at medium to high density, while SPT works in a very low density domain. These procedures all require intensive numerical computation, and the methods are tightly interwoven.

Identifiers

PMID39372265
PMCPMC11452011

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.