Evidence map›Paper›PMID 39372069›Full record

ArticleAutopsy & case reports2024

COVID-19 shed light on Virchow's law of thrombosis.

Hubert Daisley, Oneka Acco, Martina Daisley, Dennecia George, Lilly Paul, Arlene Rampersad, Johann Daisley

Abstract read
In one paragraph

Article in Autopsy & case reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Hubert DaisleyGeneral Hospital, Department of Pathology, San Fernando, Trinidad and Tobago.ORCID 0000-0002-7337-8050
Oneka AccoThe University of the West Indies, Department of Pathology, Mona, Jamaica.ORCID 0000-0003-0758-8129
Martina DaisleyPrinces Alexandra Hospital, Accident and Emergency Department The Valley, Anguilla.ORCID 0000-0001-9785-3648
Dennecia GeorgeScarborough General Hospital, Department of Pathology, Signal Hill, Trinidad and Tobago.ORCID 0009-0003-0905-4240
Lilly PaulThe University of the West Indies, Department of Pathology, Mona, Jamaica.ORCID 0000-0002-9061-9565
Arlene RampersadGeneral Hospital, Department of Pathology, San Fernando, Trinidad and Tobago.ORCID 0000-0002-4112-753X
Johann DaisleyScarborough General Hospital, Department of Pathology, Signal Hill, Trinidad and Tobago.ORCID 0000-0003-2344-7991

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Virchow's law of thrombosis states that thrombosis in a vessel occurs as a combination of the following: (i) injury to the vessel wall, (ii) stasis of blood flow, and (iii) blood hypercoagulability. Injury to the wall includes infection/inflammation and/or injury to the resident cells of the wall. We postulate that in COVID-19, the SARS-CoV-2 virus directly infects the alveolar type II cell or directly or indirectly infects/injures the pericyte, promoting inflammation and interaction with endothelial cells, thereby causing a cascade of events leading to our observation that thrombosis occurred within the walls of the pulmonary vessels and not in the lumen of the vascular circulation.

Indexed as

Blood vesselsCOVID-19Thrombosis

Identifiers

PMID39372069
PMCPMC11452080

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.