ReviewCureus2024
Edward Jenner: The Pioneer of Vaccination and His Enduring Legacy in Modern Medicine.
Review in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Smart nanoparticle vaccines integrate nanotechnology artificial intelligence and immunoengineering for precision immunization.Discover nano · 2026Review
- Ferroptosis and immunity: rewiring the tumor microenvironment for therapy.RSC advances · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Edward Jenner's work in the latter part of the 18th century laid the groundwork for contemporary vaccination techniques and represented a crucial moment in the battle against contagious diseases. Born in 1749 in Berkeley, Gloucestershire, Jenner received early medical training under the guidance of John Hunter, a distinguished British surgeon. Although variolation offered some immunity to smallpox, it was a hazardous procedure that could result in severe illness or even death. It was within the context of limited and hazardous medical practices that Jenner made his revolutionary observation that milkmaids who had contracted cowpox, a relatively mild illness, appeared to be immune to smallpox. This local folklore piqued Jenner's interest, leading him to investigate the potential of cowpox as a safer alternative to variolation. His work paved the way for the development of vaccines for other infectious diseases, transforming public health and establishing a foundation for modern immunology. The smallpox vaccine became a crucial element of public health initiatives, ultimately leading to the global eradication of the disease by the late 20th century. Jenner's contributions have saved countless lives and represent a testament to the enduring influence of his work on global health. His pioneering efforts laid the groundwork for vaccines that protect us today, solidifying his place as one of the most influential figures in medical history.
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Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.