Evidence map›Paper›PMID 39371817›Full record

ArticleCureus2024

Probable Causative Agents and Demographic Patterns of Encephalitis, Meningitis, and Meningoencephalitis in a Single Tertiary Care Center.

Ahmed Attar, Abdulrahman M Khojah, Abdulrazak M Sakhakhni, Hussam Alasmari, Abdulaziz Bamusa, Yousef Alharbi, Talal Alajmi, Mohamed E Ahmed, Abdullah A Awadh

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ahmed AttarDepartment of Neurosciences, Ministry of the National Guard - Health Affairs, Jeddah, SAU.
Abdulrahman M KhojahCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Riyadh, SAU.
Abdulrazak M SakhakhniDepartment of Critical Care Medicine, Ministry of the National Guard - Health Affairs, Jeddah, SAU.
Hussam AlasmariCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Abdulaziz BamusaCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Yousef AlharbiCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Talal AlajmiCollege of Medicine, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.
Mohamed E AhmedDepartment of Biostatistics, King Abdullah International Medical Research Center, Jeddah, SAU.
Abdullah A AwadhCollege of Basic Medical Science, King Saud Bin Abdulaziz University for Health Sciences, Jeddah, SAU.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction Encephalitis, meningitis, and meningoencephalitis present significant challenges in clinical management owing to their diverse etiologies and potential complications. A high suspicion index is critical for guiding treatment strategies and improving patient outcomes. Understanding the demographic characteristics and frequency of causes of these conditions is essential to deliver optimized care. Objective This study aimed to investigate epidemiological causes and relative outcomes, including mortality, based on cultures, laboratory investigations, and demographic factors among patients with encephalitis, meningitis, and meningoencephalitis in a Saudi Arabian tertiary care center. Methods A retrospective cross-sectional study was conducted at King Abdulaziz Medical City (KAMC) in Jeddah, Saudi Arabia. Data were collected from patients admitted between April 2016 and December 2022 who met the specified inclusion criteria. Results Among 233 patients, meningitis was the most prevalent diagnosis (65.77%), with bacterial agents being the predominant causative agents (79.74%). Higher mortality was significant with pediatrics <5 years and adults >60 years. Conclusion This study provides valuable insights into the epidemiology and clinical outcomes of central neurological infections based on a Saudi Arabian cohort. These findings underscore the importance of an accurate diagnosis and tailored management strategies. Further studies are warranted to enhance our understanding and to inform more predictable characteristics targeted in optimizing healthcare delivery for patients with such conditions.

Indexed as

acute encephalitisbacterial cns infectioncomplicated meningitissaudi populationviral cns infection

Identifiers

PMID39371817
PMCPMC11455292

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.