Evidence map›Paper›PMID 39371775›Full record

ArticleCureus2024

A Three-Year Longitudinal Follow-Up Study: Does Mild Cognitive Impairment Accelerate Age-Related Changes in Physical Function and Body Composition?

Hyuma Makizako, Shoma Akaida, Mana Tateishi, Daijo Shiratsuchi, Ryoji Kiyama, Takuro Kubozono, Toshihiro Takenaka, Mitsuru Ohishi

Abstract read
In one paragraph

Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Hyuma MakizakoDepartment of Physical Therapy, Kagoshima University, Kagoshima, JPN.
Shoma AkaidaGraduate School of Health Sciences, Kagoshima University, Kagoshima, JPN.
Mana TateishiDepartment of Epidemiology of Aging, National Center for Geriatrics and Gerontology, Obu, JPN.
Daijo ShiratsuchiGraduate School of Health Sciences, Kagoshima University, Kagoshima, JPN.
Ryoji KiyamaDepartment of Physical Therapy, Kagoshima University, Kagoshima, JPN.
Takuro KubozonoDepartment of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, JPN.
Toshihiro TakenakaDepartment of Internal and Cardiovascular Medicine, Tarumizu Chuo Hospital, Tarumizu Municipal Medical Center, Tarumizu, JPN.
Mitsuru OhishiDepartment of Cardiovascular Medicine and Hypertension, Graduate School of Medical and Dental Sciences, Kagoshima University, Kagoshima, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Age-related declines in physical function, body composition, and cognitive function are interrelated. This prospective study aimed to examine the impact of mild cognitive impairment (MCI) on age-related changes in physical function and body composition among community-dwelling older adults. We analyzed data from 180 older adults (aged ≥70 years) who completed a longitudinal assessment of physical function and body composition in the community. Physical function included grip strength and time taken to walk 10 m at normal and maximum pace. Body composition assessments calculated the body mass index (BMI) and appendicular skeletal muscle index (ASMI) using bioelectrical impedance analysis at baseline and three-year follow-up assessments. MCI was defined as values below the age- and education-adjusted reference threshold in several tests, including memory, attention, executive function, and processing speed. Participants were divided into the MCI and non-MCI groups based on their MCI status at baseline. A two-way repeated-measures analysis of covariance (ANCOVA), adjusting for age and gender, was used to analyze the group (MCI and non-MCI) by time (baseline and three-year follow-up) interaction. Thirty participants (16.7%) had MCI at baseline. The repeated-measures ANCOVA indicated that no variables had significant group by time interactions. Stratified analyses by gender (repeated-measures ANCOVA, adjusted for age) confirmed a significant group by time interaction on BMI (F=5.63, p=0.02) and ASMI (F=6.33, p=0.01) among women. Older women with MCI may experience a greater impact of the acceleration of shrinking and age-related decline in muscle mass. The close associations of MCI with shrinking and muscle mass loss have important implications for targeting interventions among MCI women.

Indexed as

agingcognitionlongitudinal studymuscle massshrinking

Identifiers

PMID39371775
PMCPMC11452312

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.