ArticleCureus2024
Harlequin Ichthyosis Nanobubble Hydrotherapy: A Breakthrough in Treatment.
Article in Cureus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Micro-Nano Bubbles: A New Field of Eco-Friendly Cleaning.Nanomaterials (Basel, Switzerland) · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This case report details the management of a 10-year-old female pediatric patient with Harlequin ichthyosis (HI), a challenging skin disorder characterized by the production of 40 times the normal skin without trifats, leading to recurrent splits and fissures. Conventional treatments were ineffective until the introduction of nanobubbles. Encouraged by successful cases, the family engaged in a 100-hour medical trial conducted three days a week at the dermatologist's office, witnessing positive outcomes after the initial 20-minute session. The nanobubble's success inspired the creation of the White Water Company in 2016, developing the first portable nanobubbler. Nanobubble technology not only addressed excessive skin production but also played a crucial role in biofilm remediation, offering a solution to an additional challenge. The 100-hour medical trial demonstrated commitment to the patient's well-being. The nanobubble bath completed the scratch-itch cycle by shedding skin during the bath and moisturizing the skin from the inside out, providing a holistic solution to the challenges posed by HI.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.