Evidence map›Paper›PMID 39371517›Full record

ArticlePreventive nutrition and food science2024

Protective Responses of Green Yuja Peel Extracts to Lipopolysaccharide-Induced Inflammation and Reactive Oxygen Species Production in RAW264.7 Cells.

Sungjin Kim, Soo-Young Choi, Hae-In Lee, Mi-Kyung Lee

Abstract read
In one paragraph

Article in Preventive nutrition and food science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Anti-obesity effects of ethanol extract of greenNutrition research and practice · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sungjin Kim *Suncheon Research Center for Bio Health Care, Jeonnam 57962, Korea.ORCID https://orcid.org/0009-0003-4146-4717
Soo-Young Choi *Department of Food and Nutrition, Sunchon National University, Jeonnam 57922, Korea.ORCID https://orcid.org/0009-0001-5011-8918
Hae-In LeeDepartment of Food and Nutrition, Sunchon National University, Jeonnam 57922, Korea.ORCID https://orcid.org/0000-0003-0221-2253
Mi-Kyung LeeDepartment of Food and Nutrition, Sunchon National University, Jeonnam 57922, Korea.ORCID https://orcid.org/0000-0002-6064-5295

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study assessed the anti-inflammatory and antioxidant effects of green yuja peel hot water extract (GYW) and ethanol extract (GYE) on lipopolysaccharide (LPS)-stimulated RAW264.7 cells. GYW and GYE (50, 100, and 200 μg/mL) significantly reduced the LPS-induced production of nitric oxide (NO), interleukin (IL)-6, tumor necrosis factor-α (TNF-α), and reactive oxygen species in a concentration-dependent manner, without cytotoxicity. Compared with control cells, GYW and GYE significantly downregulated the protein levels of inducible NO synthase (iNOS) and cyclooxygenase-2 (COX-2) and the gene expression of

Indexed as

green yuja peelinflammationlipopolysaccharidesmacrophagesreactive oxygen species

Identifiers

PMID39371517
PMCPMC11450282

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.