Evidence map›Paper›PMID 39371254›Full record

ArticleTransfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie2024

HPA1-29w Genotyping and the Foundation for the Platelet Apheresis Registry in Jiangsu Province of China by MassARRAY Spectrometry.

Xin Dai, Chengcheng Liu, Rong Chen, Ting Jiang, Ruoyang Zhang, Chenchen Feng, Taixiang Liu, Hong Lü, Wenbiao Liang

Abstract read
In one paragraph

Article in Transfusion medicine and hemotherapy : offizielles Organ der Deutschen Gesellschaft fur Transfusionsmedizin und Immunhamatologie, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

Xin DaiJiangsu Province Blood Center, Nanjing, China.
Chengcheng LiuJiangsu Xiansheng Medical Diagnosis Co., Ltd, Nanjing, China.
Rong ChenJiangsu Province Blood Center, Nanjing, China.
Ting JiangJiangsu Province Blood Center, Nanjing, China.
Ruoyang ZhangJiangsu Province Blood Center, Nanjing, China.
Chenchen FengJiangsu Province Blood Center, Nanjing, China.
Taixiang LiuJiangsu Province Blood Center, Nanjing, China.
Hong LüJiangsu Xiansheng Medical Diagnosis Co., Ltd, Nanjing, China.
Wenbiao LiangJiangsu Province Blood Center, Nanjing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: This study aimed to investigate the allele frequencies of the human platelet antigens (HPA) Methods: HPA genotyping was performed using the MassARRAY iPLEX Results: The HPA allele frequencies in the Jiangsu Han population of HPA-1b, -2b, -3b, -4b, -5b, -6b, -11b, -15b, and -21b were 0.0055, 0.0530, 0.4116, 0.0015, 0.0155, 0.0162, 0.0003, 0.4683, and 0.0070, respectively, in which a heterozygote of HPA-11a/b was first detected in China. Only allele a was detected for HPA-7-10w,-12-14w,-16-20w, and -22-29w quasi-systems. The highest mismatch rate of HPA genes in 1,640 platelet donors was the HPA-15 system, followed by the HPA-3 system with a rate of 37.4% and 36.71%, respectively. Conclusion: China's largest-scale platelet registry of HPA-1-29w has been explored. The MassARRAY platform may help found the platelet apheresis registry which would be useful to provide matching platelets and lead to a more accurate, effective, and safe transfusion for patients with platelet therapy.

Indexed as

Allele frequencyChinese Han populationHuman platelet alloantigenMassARRAY spectrometryPlatelet apheresis registry

Identifiers

PMID39371254
PMCPMC11452151

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.