Evidence map›Paper›PMID 39370944›Full record

Trial reportJournal of genetic counseling2025

Randomized control trial comparing genetic counseling service delivery models in an underserved population.

Sayoni Lahiri, Jacqueline Mersch, John Zimmerman, Caitlin Mauer Hall, Kelsey Moriarty, Amber Gemmell, MinJae Lee, Cheyla Clark, Michelle Luong, Caroline Stokes and 3 more

Abstract readComparative StudyRandomized Controlled Trial
In one paragraph

Trial report in Journal of genetic counseling, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Large-Scale Population Screening forBreast care (Basel, Switzerland) · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Sayoni LahiriSimmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.
Jacqueline MerschSimmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.
John ZimmermanSimmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.
Caitlin Mauer HallSimmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.
Kelsey MoriartySimmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.
Amber GemmellSimmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.
MinJae LeeSimmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.
Cheyla ClarkSimmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.
Michelle LuongSimmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.
Caroline StokesSimmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.
Kathryn RomanoSimmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.
Cynthia A JamesDivision of Cardiology, Johns Hopkins School of Medicine, Baltimore, Maryland, USA.
Sara Pirzadeh-MillerSimmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas, USA.ORCID 0000-0001-6731-378X

Funding

UT Southwestern Medical Center Simmons Comprehensive Cancer CenterP30CA142543 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI MELANIE H. COBB · 2010 to 2026
$53.7M
National Society of Genetic CounselorsNCI NIH HHS P30 CA142543
6 · The paper itself

Abstract

This randomized controlled trial compares outcomes of telephone versus in-person genetic counseling service models in underserved, bilingual patient populations referred for cancer genetic counseling. Between 2022 and 2023, a two-arm (telephone vs. in-person genetic counseling) prospective, randomized controlled study with 201 participants was conducted at two county hospital cancer genetics clinics. Primary outcomes included comparison of pre- and post-genetic counseling genetics knowledge (Multi-dimensional Model of Informed Choice, MMIC), genetic counseling visit satisfaction (Genetic Counseling Satisfaction Scale, GCSS), and genetic counseling visit completion rates. Secondary outcomes included comparison of genetic testing attitudes and informed choice (MMIC), genetic counseling-specific empowerment (Genomic Outcomes Scale, GOS), and genetic testing completion and cancellation/failure rates, using linear regression models (significance ≤0.05). There were no statistically significant differences between arms in pre/post-genetic counseling MMIC knowledge and attitude, GOS or GCSS scores or genetic counseling completion. While more participants in the telephone versus in-person arm made an informed choice about testing (52.5% v. 39.0%, p = 0.0552), test completion was lower (74% v. 100%, p < 0.05) for this group. Genetic counseling completion rates and MMIC knowledge and attitude, GOS, and GCSS scores suggest telephone genetic counseling is comparable to in-person genetic counseling for underserved populations. Higher informed choice scores and significantly lower testing completion rates for telephone visits require further study.

Indexed as

Genetic CounselingTelephoneVulnerable PopulationsAdultFemaleHumansMaleMiddle AgedProspective Studiesdisparitiesgenetic counselinggenetics servicesoutcomesservice delivery modelsunderrepresented populations

Identifiers

PMID39370944
PMCPMC11866741

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.