Evidence map›Paper›PMID 39370744›Full record

ArticleJournal of biological rhythms2024

The Reindeer Circadian Clock Is Rhythmic and Temperature-compensated But Shows Evidence of Weak Coupling Between the Secondary and Core Molecular Clock Loops.

Daniel Appenroth, Chandra S Ravuri, Sara K Torppa, Shona H Wood, David G Hazlerigg, Alexander C West

Abstract read
In one paragraph

Article in Journal of biological rhythms, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Direct Temperature Responses ofJournal of biological rhythms · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel AppenrothArctic Seasonal Timekeeping Initiative, Arctic Chronobiology and Physiology Research Group, Department of Arctic and Marine Biology, UiT-The Arctic University of Norway, Tromsø, Norway.ORCID 0000-0003-0197-3739
Chandra S RavuriArctic Seasonal Timekeeping Initiative, Arctic Chronobiology and Physiology Research Group, Department of Arctic and Marine Biology, UiT-The Arctic University of Norway, Tromsø, Norway.
Sara K TorppaArctic Seasonal Timekeeping Initiative, Arctic Chronobiology and Physiology Research Group, Department of Arctic and Marine Biology, UiT-The Arctic University of Norway, Tromsø, Norway.ORCID 0009-0002-6835-1192
Shona H WoodArctic Seasonal Timekeeping Initiative, Arctic Chronobiology and Physiology Research Group, Department of Arctic and Marine Biology, UiT-The Arctic University of Norway, Tromsø, Norway.ORCID 0000-0002-8273-4045
David G HazleriggArctic Seasonal Timekeeping Initiative, Arctic Chronobiology and Physiology Research Group, Department of Arctic and Marine Biology, UiT-The Arctic University of Norway, Tromsø, Norway.
Alexander C WestArctic Seasonal Timekeeping Initiative, Arctic Chronobiology and Physiology Research Group, Department of Arctic and Marine Biology, UiT-The Arctic University of Norway, Tromsø, Norway.ORCID 0000-0003-3934-5068

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Circadian rhythms synchronize the internal physiology of animals allowing them to anticipate daily changes in their environment. Arctic habitats may diminish the selective advantages of circadian rhythmicity by relaxing daily rhythmic environmental constraints, presenting a valuable opportunity to study the evolution of circadian rhythms. In reindeer, circadian control of locomotor activity and melatonin release is weak or absent, and the molecular clockwork is reportedly non-functional. Here we present new evidence that the circadian clock in cultured reindeer fibroblasts is rhythmic and temperature-compensated. Compared with mouse fibroblasts, however, reindeer fibroblasts have a short free-running period, and temperature cycles have an atypical impact on clock gene regulation. In reindeer cells,

Indexed as

ARNTL Transcription FactorsCircadian ClocksCircadian RhythmFibroblastsPeriod Circadian ProteinsReindeerTemperatureAnimalsCells, CulturedGene Expression RegulationMelatoninMiceMotor ActivityPromoter Regions, GeneticARNTL Transcription FactorsMelatoninPeriod Circadian Proteinscell culturecircadianentrainmentpolarRangifer tarandusreindeertemperature compensation

Identifiers

PMID39370744
PMCPMC11613641

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.