ArticleBJOG : an international journal of obstetrics and gynaecology2025
The Contribution of Hypertensive Disorders of Pregnancy to Neonatal Unit Admissions and Iatrogenic Preterm Delivery at < 34
Article in BJOG : an international journal of obstetrics and gynaecology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Association of borderline hypertension defined by ACC-AHA diagnostic criteria during pregnancy with neurodevelopment in infants.BMC medicine · 2026Article
- Relationship between hypertensive disorders of pregnancy and postpartum mood and anxiety symptoms: P4 study.Archives of women's mental health · 2026Observational
- Long-term mortality in women with a history of hypertensive disorders of pregnancy: a systematic review and meta-analysis.EClinicalMedicine · 2026Article
- Term neonatal admissions for hypoglycaemia in England and Wales, 2012-2020: a population-based study using the National Neonatal Research Database.Archives of disease in childhood. Fetal and neonatal edition · 2026Article
- Global, regional, and national trends and burden of hypertensive disorders in pregnancy among women of childbearing age from 1990 to 2021.Frontiers in global women's health · 2025Article
- Hypertensive disorders of pregnancy increase neonatal cerebral regional tissue oxygen saturation in the early postnatal period: partial mediation by preterm birth.Frontiers in cell and developmental biology · 2025Article
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Authors and funding
6 authors.
Funding
Abstract
objectivesThe objectives of this study were to (i) quantify the contribution of maternal hypertensive disorders of pregnancy (HDP) to iatrogenic preterm birth (PTB) and neonatal unit (NNU) admissions < 34
designRetrospective population-based study using the National Neonatal Research Database.
settingEngland and Wales. POPULATION: Infants born < 34
methodsDescriptive statistics, linear and logistic regression models to compare outcomes between groups.
main outcome measuresSurvival to discharge with/without comorbidity.
results122 228 infants met inclusion criteria. Where collected, 49 839/114 164 (43.7%, 95% CI 43.4%-43.9%) of infants had an iatrogenic PTB. HDP was recorded in 16 510/122 228 (13.5%) of all infants and 13 560/49 839 (27.2%) of iatrogenic PTBs. HDP and/or foetal growth restriction (FGR) were recorded in 24 124/49 839 (48.4%) of iatrogenic PTBs. Singleton HDP infants < 10th BWC had ≥ 90% survival to discharge from 28 weeks' gestation, versus from 26 weeks' gestation for those born ≥ 10th BWC. In extreme preterm HDP infants (< 27 weeks), 27.3% of infants < 10th BWC died compared to 15.2% of those ≥ 10th BWC. Survival without comorbidity was ≥ 90% from 32 weeks' gestation in HDP infants across BWC.
conclusionsThese contemporaneous population-level data show that almost one in two PTB < 34
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