Observational studyColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2024
Anal sphincter function in rectal intussusception and high and low "take-off" external rectal prolapse-A prospective observational study.
Observational study in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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The trial behind it
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Who cites it
6 citing papers in PubMed.
- Functional and Anatomical Significance of Patulous Anus.Digestive diseases and sciences · 2026Article
- Thickening of the internal anal sphincter: correlation with external rectal intussusception and associated features at MR proctography and anal manometry.Abdominal radiology (New York) · 2026Article
- Anal sphincter function in conservatively managed rectal intussusception at long-term follow-up: A prospective anal acoustic reflectometry study with comparison to healthy volunteer data.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2026Article
- Transvaginal single-pathway composite reconstruction for pelvic organ prolapse combined with rectal prolapse: a case report.Frontiers in surgery · 2026Article
- MR Defecography Improves Diagnosis of Postoperative Pelvic Floor Dysfunction After Gynecological Surgery.Diagnostics (Basel, Switzerland) · 2025Review
- Anal sphincter function in rectal intussusception and high and low "take-off" external rectal prolapse-A prospective observational study.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024Observational
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
aimRectal intussusception (RI) and external rectal prolapse (ERP) are associated with anal sphincter dysfunction. The aim of this study was to examine sphincter function with anal acoustic reflectometry (AAR) in RI and two distinct phenotypes of ERP termed high and low "take-off".
methodsA prospective study of patients with RI and ERP attending a tertiary pelvic floor unit. Clinical data, AAR, and conventional anal manometry were analysed according to the Oxford prolapse grade.
resultsA total of 108 (102 [94%] female, median age 62 years [range: 26-95]) patients were recruited into three groups according to prolapse grade: Oxford grades I and II (intrarectal RI, n = 34), Oxford grades III and IV (intra-anal RI, n = 35) and Oxford grade V (ERP, n = 39). As the grade of prolapse increased, resting AAR measurements of opening pressure, opening elastance, closing pressure, and closing elastance decreased (p < 0.001). Maximum resting pressure with manometry was reduced in ERP and intra-anal RI compared to intrarectal RI (p < 0.001). However, incremental squeeze function was not different between the three groups with either AAR or manometry (p > 0.05). There were no differences in AAR or manometry variables between grade IV RI (n = 18) and high take-off ERP (n = 20) (p > 0.05). By contrast, opening pressure (p = 0.010), closing pressure (p = 0.019) and elastance (p = 0.022) were reduced in low take-off ERP (n = 19).
conclusionIncreasing rectal prolapse grade is associated with reduced anal sphincter function at rest indicating internal anal sphincter dysfunction. Physiological differences exist between high and low take-off ERP with sphincter function in the former similar to that seen in grade IV RI.
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