Evidence map›Paper›PMID 39370557›Full record

ArticleColorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland2024

Closed-incision negative-pressure wound therapy after Bascom's cleft lift surgery for pilonidal sinus disease: A randomized study comparing healing.

Ida Kaad Faurschou, Marlene Julia Sørensen, Allan Gorm Pedersen, Simon Ladefoged Rasmussen, Rune Erichsen, Susanne Haas

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Article in Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

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4citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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4 citing papers in PubMed.

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  4. Closed-incision negative-pressure wound therapy after Bascom's cleft lift surgery for pilonidal sinus disease: A randomized study comparing healing.Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland · 2024
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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Ida Kaad FaurschouDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0001-9760-5345
Marlene Julia SørensenPilonidal Disease Center, Department of Surgery, Randers Regional Hospital, Randers, Denmark.
Allan Gorm PedersenDepartment of Surgery, Horsens Regional Hospital, Horsens, Denmark.
Simon Ladefoged RasmussenPilonidal Disease Center, Department of Surgery, Randers Regional Hospital, Randers, Denmark.
Rune ErichsenDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.
Susanne HaasDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-2135-433X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimDespite favourable outcomes in recurrence after off-midline closure techniques in pilonidal surgery, between 18% and 40% of patients suffer from prolonged postoperative wound healing. The aim of this work was to investigate if closed-incision negative-pressure wound therapy (NPWT) promotes wound healing after Bascom's cleft lift (BCL) surgery for complicated pilonidal sinus disease compared with conventional drainage and dressing.

methodPatients were randomized to either NPWT for 4-7 days or loop-vessel drain for 24 h and a dry dressing postoperatively. Healing was evaluated by a wound care nurse blinded for randomization at 2 and 12 weeks postoperatively (primary endpoint). Healing was defined as one or no closing defects of ≤5 mm and with no undermining.

resultsAlthough we had wanted to recruit 200 patients, the study was terminated at 118 patients (NPWT group, n = 60; control group, n = 58) after interim analysis. Patients were comparable by age, sex, body mass index, previous smoking status and indication for BCL surgery. At 2 weeks 12% of patients were healed in both the NPWT and control groups [risk difference = 0.00(95% CI -0.12 to 0.11), p = 1.00]. After 12 weeks, 68% of patients were healed in the NPWT group and 72% in the control group [risk difference = -0.03 (95% CI 0.19 to 0.13), p = 0.82]. There was no significant difference in pain experienced postsurgery. In a symptom-based questionnaire, the control group reported self-esteem to be less affected (p = 0.015).

conclusionClosed-incision negative-pressure wound therapy did not significantly improve healing after BCL surgery for complicated pilonidal sinus disease.

Indexed as

Bascom cleft liftciNPTcleft lift surgerynegative‐pressure wound therapynon‐healing woundpilonidal diseasepilonidal sinuspilonidal sinus diseasepilonidal surgeryrecurrent pilonidal diseasesurgical flapsvacuum‐assisted closure

Identifiers

PMID39370557
PMCPMC11683170

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.