Evidence map›Paper›PMID 39370518›Full record

ReviewJournal of nanobiotechnology2024

Biomimetic nanocarriers in cancer therapy: based on intercellular and cell-tumor microenvironment communication.

He Mengyuan, Li Aixue, Gu Yongwei, Chai Qingqing, Cai Huanhuan, Liu Xiaoyan, Liu Jiyong

Abstract readReview
In one paragraph

Review in Journal of nanobiotechnology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

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  19. Nanovaccines in gastrointestinal cancers.Frontiers in immunology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

He Mengyuan *College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Li Aixue *College of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Gu YongweiDepartment of Pharmacy, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Chai QingqingDepartment of Pharmacy, Fudan University Shanghai Cancer Center, Shanghai, 200032, China.
Cai HuanhuanCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China.
Liu XiaoyanDepartment of Pharmacy, Huadong Hospital, Fudan University, Shanghai, 200040, China. xiaoyan5156@163.com.
Liu JiyongCollege of Pharmacy, Shandong University of Traditional Chinese Medicine, Jinan, 250355, China. liujiyong@fudan.edu.cn.

Funding

Cooperation Program of the Xuhui District Medical College with Enterprises 23XHYD-24National Key Research and Development Program of China 2023YFC3404103National Natural Science Foundation of China 82274103Program of Shanghai Academic Research Leader 21XD1403400Science and Technology Commission of Shanghai Municipality 23S21900200
6 · The paper itself

Abstract

Inspired by the concept of "natural camouflage," biomimetic drug delivery systems have emerged to address the limitations of traditional synthetic nanocarriers, such as poor targeting, susceptibility to identification and clearance, inadequate biocompatibility, low permeability, and systemic toxicity. Biomimetic nanocarriers retain the proteins, nucleic acids, and other components of the parent cells. They not only facilitate drug delivery but also serve as communication media to inhibit tumor cells. This paper delves into the communication mechanisms between various cell-derived biomimetic nanocarriers, tumor cells, and the tumor microenvironment, as well as their applications in drug delivery. In addition, the additional communication capabilities conferred on the modified biomimetic nanocarriers, such as targeting and environmental responsiveness, are outlined. Finally, we propose future development directions for biomimetic nanocarriers, hoping to inspire researchers in their design efforts and ultimately achieve clinical translation.

Indexed as

Biomimetic MaterialsDrug CarriersNanoparticlesNeoplasmsTumor MicroenvironmentAnimalsAntineoplastic AgentsBiomimeticsCell CommunicationDrug Delivery SystemsHumansAntineoplastic AgentsDrug CarriersBiomimetic nanocarriersCancerCommunicationMicroenvironment

Identifiers

PMID39370518
PMCPMC11456251

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.