Evidence map›Paper›PMID 39370347›Full record

ArticlePain management nursing : official journal of the American Society of Pain Management Nurses2025

A Scoping Review of Social Determinants of Health and Pain Outcomes in Sickle Cell Disease.

Juanita E Darby, Ivy C Akpotu, Dahee Wi, Sarah Ahmed, Ardith Z Doorenbos, Saria Lofton

Abstract readScoping Review
In one paragraph

Article in Pain management nursing : official journal of the American Society of Pain Management Nurses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Juanita E DarbyCollege of Nursing, University of Illinois Chicago, Chicago, IL. Electronic address: jdarby4@uic.edu.
Ivy C AkpotuCollege of Nursing, University of Illinois Chicago, Chicago, IL.
Dahee WiCollege of Nursing, University of Illinois Chicago, Chicago, IL.
Sarah AhmedCollege of Nursing, University of Illinois Chicago, Chicago, IL.
Ardith Z DoorenbosCollege of Nursing, University of Illinois Chicago, Chicago, IL.
Saria LoftonCollege of Nursing, University of Illinois Chicago, Chicago, IL.

Funding

Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease PainUH3AT011265 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DOORENBOS, ARDITH Z, EZENWA, MIRIAM OMELEBELE · 2021 to 2024
$6.4M
Hybrid Effectiveness-Implementation Trial of Guided Relaxation and Acupuncture for Chronic Sickle Cell Disease PainUG3AT011265 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DOORENBOS, ARDITH Z, EZENWA, MIRIAM OMELEBELE · 2020 to 2020
$827k
Providing training in effective non-opioid options for the treatment of pain conditions.K24AT011995 · NCCIH · UNIVERSITY OF ILLINOIS AT CHICAGO · PI DOORENBOS, ARDITH Z · 2021 to 2021
$324k
NCCIH NIH HHS K24 AT011995NCCIH NIH HHS UG3 AT011265NCCIH NIH HHS UH3 AT011265
6 · The paper itself

Abstract

backgroundSickle cell disease (SCD) is a hereditary blood disorder with chronic pain that affects over 100,000 people in the United States. Previous research suggests a complex interaction between SCD pain outcomes and social determinants of health (SDOH).

objectiveTo explore the impact of SDOH on pain outcomes in SCD.

designWe used a scoping review design to explore the broad topic of social factors that affect SCD pain. DATA SOURCES: We searched the PubMed/MEDLINE, CINAHL, and Embase databases using combined search and Medical Subject Headings terms ("social determinants of health," "sickle cell," and "pain"). REVIEW

methodsWe used a content analysis with a summative approach to identify and describe interactions between SDOH and SCD pain outcomes.

findingsEight articles reporting studies with 7,992 total participants and a focus on SCD pain outcomes met the inclusion criteria. Three themes related to SDOH and pain were produced: education and employment, social and emotional functioning, and healthcare access.

conclusionThe key findings highlight the complex interplay between socioeconomic, psychological, and biological factors in SCD pain experiences. This underscores the need for nursing care to consider SDOH in an integrated, holistic approach to SCD pain. IMPLICATIONS FOR NURSING: To improve pain management among their SCD patients, nurses can assess pain holistically, develop customized individual pain management plans with educational and health literacy support options, and strengthen social support.

Indexed as

Anemia, Sickle CellSocial Determinants of HealthChronic PainHumansPain ManagementHealth inequitiesHealth status disparitiesPain managementSickle cell diseaseSocial determinants of health

Identifiers

PMID39370347
PMCPMC13686787

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.