Evidence map›Paper›PMID 39370257›Full record

ArticleInternal medicine (Tokyo, Japan)2025

An Unusual Case of a Central Pontine Myelinolysis Associated with Primary Splenic Diffuse Large B-cell Lymphoma.

Masayoshi Yamasaki, Akira Taniguchi, Hirohito Minami, Tomoko Tada, Tadashi Yabana, Yutaka Naito

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masayoshi YamasakiDepartment of Neurology, Japanese Red Cross Ise Hospital, Japan.
Akira TaniguchiDepartment of Neurology, Japanese Red Cross Ise Hospital, Japan.
Hirohito MinamiDepartment of Hematology, Japanese Red Cross Ise Hospital, Japan.
Tomoko TadaDepartment of Cardiology, Japanese Red Cross Ise Hospital, Japan.
Tadashi YabanaDepartment of Pathology, Japanese Red Cross Ise Hospital, Japan.
Yutaka NaitoDepartment of Neurology, Japanese Red Cross Ise Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 54-year-old woman with persistent fatigue and a high fever presented with central pontine myelinolysis (CPM) on brain imaging, despite the absence of neurological symptoms. The patient had a slightly low serum sodium concentration. Further investigation led to a diagnosis of primary splenic diffuse large B-cell lymphoma (PS-DLBCL). Brainstem auditory-evoked potentials (BAEP) indicated minor abnormalities. CPM was successfully resolved after splenectomy and immunochemotherapy. This is the first reported case of CPM in a patient with PS-DLBCL confirmed by a pathological diagnosis following splenectomy and BAEP-detected abnormalities that improved with immunochemotherapy.

Indexed as

Lymphoma, Large B-Cell, DiffuseMyelinolysis, Central PontineSplenic NeoplasmsAntineoplastic Combined Chemotherapy ProtocolsEvoked Potentials, Auditory, Brain StemFemaleHumansMagnetic Resonance ImagingMiddle AgedSplenectomybrainstem auditory evoked potentialcentral pontine myelinolysismalignant lymphomaprimary splenic diffuse large B-cell lymphomaR-CHOPsplenectomy

Identifiers

PMID39370257
PMCPMC12183411

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.