Evidence map›Paper›PMID 39370251›Full record

ArticleInternal medicine (Tokyo, Japan)2025

Cognitive Impairment Caused by Isolated Adrenocorticotropic Hormone Deficiency Mimicking Dementia with Lewy Bodies.

Ryuji Yajima, Yasuharu Saito, Takeshi Sato, Akiko Suzuki, Satoshi Naruse

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Internal medicine (Tokyo, Japan), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ryuji YajimaDepartment of Neurology, Midori Hospital, Japan.
Yasuharu SaitoDepartment of Internal Medicine, Midori Hospital, Japan.
Takeshi SatoDepartment of Internal Medicine, Midori Hospital, Japan.
Akiko SuzukiDepartment of Diabetology, Endocrinology and Metabolism, Niigata Bandai Hospital, Japan.
Satoshi NaruseDepartment of Neurology, Midori Hospital, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A 73-year-old man who presented with nonspecific general symptoms and cognitive impairment was initially diagnosed with mild cognitive impairment due to dementia with Lewy bodies (DLB) based on a reduced blood flow in the parietal and occipital lobes on single-photon emission computed tomography (SPECT) imaging. However, the patient later presented with hyponatremia and hypoglycemia, leading to impaired consciousness, and was diagnosed with isolated adrenocorticotropic hormone deficiency (IAD). Hydrocortisone treatment improved the blood test scores and general symptoms, including cognitive impairment. IAD may show a DLB-like presentation on cerebral blood flow SPECT; therefore, caution is required for the correct diagnosis of IAD.

Indexed as

Adrenal InsufficiencyAdrenocorticotropic HormoneCognitive DysfunctionEndocrine System DiseasesLewy Body DiseaseAgedDiagnosis, DifferentialGenetic Diseases, InbornHumansHydrocortisoneHypoglycemiaMaleTomography, Emission-Computed, Single-PhotonAdrenocorticotropic HormoneHydrocortisoneadrenal insufficiencycognitive impairmentdementia with Lewy bodiesisolated adrenocorticotropic hormone deficiencytreatable dementia

Identifiers

PMID39370251
PMCPMC12120212

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.