Evidence map›Paper›PMID 39369277›Full record

ReviewAlzheimer's & dementia : the journal of the Alzheimer's Association2024

Argentina-Alzheimer's Disease Neuroimaging Initiative: pioneering Alzheimer's Research in Latin America and its Implications for Regional Advancement.

Jonathan Fernando Cubas Guillen, Patricio Chrem Méndez, Ezequiel Surace, María Eugenia Martin, Florencia Clarens, Julieta Russo, Paula Harris, Noelia Egido, Fernanda Tapajoz, Hernán Chaves and 6 more

Abstract readReview
In one paragraph

Review in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. The landscape of dementia research, diagnosis, treatment, and care in Latin America.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors.

Jonathan Fernando Cubas GuillenDepartment of Cognitive Neurology, Neuropsychology and Neuropsychiatry, Instituto Neurológico Fleni, Buenos Aires, Argentina.ORCID 0000-0001-5257-6720
Patricio Chrem MéndezDepartment of Cognitive Neurology, Neuropsychology and Neuropsychiatry, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Ezequiel SuraceDepartment of Molecular Biology, Instituto Neurológico Fleni, Buenos Aires, Argentina.
María Eugenia MartinDepartment of Cognitive Neurology, Neuropsychology and Neuropsychiatry, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Florencia ClarensDepartment of Cognitive Neurology, Neuropsychology and Neuropsychiatry, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Julieta RussoDepartment of Cognitive Neurology, Neuropsychology and Neuropsychiatry, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Paula HarrisDepartment of Cognitive Neurology, Neuropsychology and Neuropsychiatry, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Noelia EgidoDepartment of Cognitive Neurology, Neuropsychology and Neuropsychiatry, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Fernanda TapajozDepartment of Cognitive Neurology, Neuropsychology and Neuropsychiatry, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Hernán ChavesDepartment of Neuroimaging, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Silvia VázquezCentre of Molecular Imaging, Instituto Neurológico Fleni, Escobar, Buenos Aires, Argentina.
Horacio MartinettoDepartment of Molecular Biology, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Jorge CamposDepartment of Cognitive Neurology, Neuropsychology and Neuropsychiatry, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Ismael Luis CalandriDepartment of Cognitive Neurology, Neuropsychology and Neuropsychiatry, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Gustavo SevleverDepartment of Molecular Biology, Instituto Neurológico Fleni, Buenos Aires, Argentina.
Ricardo F AllegriDepartment of Cognitive Neurology, Neuropsychology and Neuropsychiatry, Instituto Neurológico Fleni, Buenos Aires, Argentina.ORCID 0000-0001-7166-1234

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Alzheimer's Disease Neuroimaging Initiative (ADNI) has fostered collaboration among researchers around the world, catalyzing innovation and accelerating progress in the field. In Latin America, this initiative advanced the validation and development of Alzheimer's disease biomarkers for the first time in our region. In 2011, as part of the international ADNI, Argentina-ADNI (Arg-ADNI) was founded. The following years were characterized by strong support from entities such as the Alzheimer's Association, transforming into the emergence of several multinational studies focusing on prevention and diagnosis, and treatment of dementias. These studies are heirs to the tradition of Arg-ADNI: the Dominantly Inherited Alzheimer Network, Latin American Initiative for Lifestyle Intervention to Prevent Cognitive Decline, Longitudinal Early-Onset Alzheimer's Disease Study, and Initiative for the Study of Down Syndrome and Alzheimer's Disease. These initiatives have contributed significantly to the development of regional research and serve as essential tools for health policy planning in Latin America. HIGHLIGHTS: In Latin America, the Alzheimer's Disease Neuroimaging Initiative (ADNI) advanced the validation and development of Alzheimer's disease biomarkers for the first time in our region. ADNI has been the basis that boosted several multinational studies focusing on both prevention and diagnosis, and treatment of dementias (Dominantly Inherited Alzheimer Network, LatAm-FINGER, LEADS). These initiatives with the support from the Alzheimer's Association have contributed significantly to the development of regional research This is an example of collaboration between high-income countries with low- and middle-income countries aimed at global scientific development and inclusion.

Indexed as

Alzheimer DiseaseNeuroimagingArgentinaBiomarkersCognitive DysfunctionHumansLatin AmericaBiomarkersAlzheimer's diseasebiomarkersdementia

Identifiers

PMID39369277
PMCPMC11567812

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.