Evidence map›Paper›PMID 39369249›Full record

ArticleJournal of anesthesia, analgesia and critical care2024

Lung ultrasound assessment of atelectasis following different anesthesia induction techniques in pediatric patients: a propensity score-matched, observational study.

Anna Camporesi, Giulia Roveri, Luigi Vetrugno, Danilo Buonsenso, Valentina De Giorgis, Sara Costanzo, Ugo Maria Pierucci, Gloria Pelizzo

3 registry-linked trialsAbstract read
In one paragraph

Article in Journal of anesthesia, analgesia and critical care, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 3 registered trials, which are not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06069414 completednot on this map

Atelectasis Evaluated With Lung Ultrasound After Inhalation or Intravenous Induction in Pediatric Anesthesia: a Prospective, Observational, Propensity Scored Matched Study

TypeobservationalSponsorVittore Buzzi Children's HospitalRan2023 to 2023Enrolled326ConditionsAtelectasis, Pediatric AnesthesiaArmsType of anesthesia induction
NCT07042854 completednot on this map

Volume-Controlled vs Pressure-Regulated Volume Control Ventilation in Pediatric Anesthesia: an Electrical Impedance Tomography Based Study

TypeobservationalSponsorVittore Buzzi Children's HospitalRan2024 to 2025Enrolled123ConditionsVentilation Homogeneity, Anesthesia
NCT07182539 nanot yet recruitingnot on this mapstarted 2025, after this paper: background citation

Atelectasis in Pediatric Anesthesia: A Randomized Observational Study Comparing Volume-Controlled and Pressure-Regulated Volume Control Ventilation Via Lung Ultrasound and Electrical Impedance Tomography

TypeinterventionalSponsorVittore Buzzi Children's HospitalRan2025 to 2026Enrolled88ConditionsAtelectasisArmsPRVC ventilation, VCV ventilation
3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Article
  5. Anaesthesia-induced atelectasis in a rat model (Frontiers in veterinary science · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Anna Camporesi *Department of Pediatric Anesthesia and Intensive Care, Buzzi Children's Hospital, Via Castelvetro 32, 20154, Milan, Italy. anna.camporesi@gmail.com.ORCID http://orcid.org/0000-0002-1160-1456
Giulia Roveri *Department of Anesthesia and Intensive Care Medicine "F. Tappeiner" Hospital, Merano, Italy.
Luigi VetrugnoDepartment of Medical, Oral and Biotechnological Sciences, University of Chieti-Pescara, Chieti, Italy.
Danilo BuonsensoDepartment of Woman and Child Health and Public Health, Fondazione Policlinico Universitario "A. Gemelli", Rome, Italy.
Valentina De GiorgisDepartment of Pediatric Anesthesia and Intensive Care, Buzzi Children's Hospital, Via Castelvetro 32, 20154, Milan, Italy.
Sara CostanzoPediatric Surgery Department, Buzzi Children's Hospital, Milan, Italy.
Ugo Maria Pierucci *Pediatric Surgery Department, Buzzi Children's Hospital, Milan, Italy.
Gloria Pelizzo *Pediatric Surgery Department, Buzzi Children's Hospital, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAtelectasis is a well-documented complication in pediatric patients undergoing general anesthesia. Its incidence varies significantly based on surgical procedures and anesthesia techniques. Inhalation induction, commonly used to avoid the discomfort of venipuncture, is suspected to cause higher rates of respiratory complications, including atelectasis, compared to intravenous induction. This study aimed to evaluate the impact of inhalation versus intravenous anesthesia induction on atelectasis formation in pediatric patients, as assessed by lung ultrasound (LUS).

methodsThis propensity score-matched observational study was conducted at a tertiary pediatric hospital in Milan, Italy. Inclusion criteria were children ≤ 18 years undergoing elective surgery with general anesthesia. Patients were divided into inhalation and intravenous induction groups. LUS was performed before and after anesthesia induction to assess lung aeration. The primary endpoint was the global LUS score post-induction, with secondary endpoints including the incidence and distribution of atelectasis.

resultsOf the 326 patients included, 65% underwent inhalation induction and 35% intravenous induction. The global LUS score was significantly higher in the inhalation group (12.0 vs. 4.0, p < 0.001). After propensity score matching (for age, presence of upper respiratory tract infection, duration of induction, and PEEP levels at induction), average treatment effect (ATE) of mask induction was 5.89 (95% CI, 3.21-8.58; p < 0.001) point on LUS global score and a coefficient of 0.35 (OR 1.41) for atelectasis. DISCUSSION: Inhalation induction is associated with a higher incidence of atelectasis in pediatric patients also when we adjusted for clinically relevant covariates.

trial registrationClinicalTrials.gov identifier: NCT06069414.

Indexed as

AtelectasisInhalatory inductionIntravenous inductionLung ultrasoundPediatric anesthesia

Identifiers

PMID39369249
PMCPMC11452973

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.