Evidence map›Paper›PMID 39369244›Full record

ArticleMolecular cancer2024

Artificial intelligence alphafold model for molecular biology and drug discovery: a machine-learning-driven informatics investigation.

Song-Bin Guo, Yuan Meng, Liteng Lin, Zhen-Zhong Zhou, Hai-Long Li, Xiao-Peng Tian, Wei-Juan Huang

Abstract read
In one paragraph

Article in Molecular cancer, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 105 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
105citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

105 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
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  16. Combatting pulmonary fibrosis withChinese herbal medicines · 2026
    Review
  17. Generative AI-drivenAntibody therapeutics · 2026
    Article
  18. Review
  19. Review
  20. Article

45 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Song-Bin Guo *Department of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, P. R. China. guosb.sysucc@yeah.net.
Yuan Meng *State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, 510060, P. R. China.
Liteng Lin *Laboratory of Interventional Radiology, Department of Minimally Invasive Interventional Radiology and Interventional Cancer Center, The Second Affiliated Hospital, Guangzhou Medical University, Guangzhou, 510260, P. R. China.
Zhen-Zhong ZhouDepartment of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, P. R. China.
Hai-Long LiDepartment of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, P. R. China.
Xiao-Peng TianDepartment of Medical Oncology, Sun Yat-Sen University Cancer Center, Guangzhou, 510060, P. R. China. tianxp@sysucc.org.cn.
Wei-Juan HuangDepartment of Pharmacology, College of Pharmacy, Jinan University, Guangzhou, 510632, P. R. China. wjhuang@jnu.edu.cn.

Funding

Guangdong Basic and Applied Basic Research Foundation 2024B1515020026National Natural Science Foundation of China 82422010
6 · The paper itself

Abstract

AlphaFold model has reshaped biological research. However, vast unstructured data in the entire AlphaFold field requires further analysis to fully understand the current research landscape and guide future exploration. Thus, this scientometric analysis aimed to identify critical research clusters, track emerging trends, and highlight underexplored areas in this field by utilizing machine-learning-driven informatics methods. Quantitative statistical analysis reveals that the AlphaFold field is enjoying an astonishing development trend (Annual Growth Rate = 180.13%) and global collaboration (International Co-authorship = 33.33%). Unsupervised clustering algorithm, time series tracking, and global impact assessment point out that Cluster 3 (Artificial Intelligence-Powered Advancements in AlphaFold for Structural Biology) has the greatest influence (Average Citation = 48.36 ± 184.98). Additionally, regression curve and hotspot burst analysis highlight "structure prediction" (s = 12.40, R

Indexed as

Artificial IntelligenceDrug DiscoveryMachine LearningAlgorithmsComputational BiologyCOVID-19HumansMolecular BiologySARS-CoV-2AlphaFoldArtificial intelligenceBibliometricsDrug discoveryMolecular dynamicsStructure prediction

Identifiers

PMID39369244
PMCPMC11452995

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.