Evidence map›Paper›PMID 39369239›Full record

ArticleTrials2024

DepActive: study protocol for a randomised controlled multicentre trial of telephone-delivered behavioural activation for the treatment of depression in older adults in primary care.

Elin Byström, Björn Wennlöf, Inger Johansson, Lena Lönnberg, Marina Arkkukangas, Johnny Pellas, Mattias Damberg

Registry-linked trialAbstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in Trials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06284889 (Behavioral Activation for the Treatment of Depression in Older Adults), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06284889 nanot yet recruitingnot on this map

Behavioral Activation for the Treatment of Depression in Older Adults: A Randomised Controlled Multicenter Trial in Primary Care (DepActive)

TypeinterventionalSponsorUppsala UniversityRan2024 to 2028Enrolled250ConditionsDepressionArmsBehavioural activation, Treatment as usual (TAU)
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elin ByströmRegion Vastmanland - Uppsala University Centre for Clinical Research, Vastmanland Hospital Vasteras, Västerås, Sweden. elin.bystrom@regionvastmanland.se.ORCID http://orcid.org/0009-0009-2316-0334
Björn WennlöfRegion Vastmanland - Uppsala University Centre for Clinical Research, Vastmanland Hospital Vasteras, Västerås, Sweden.
Inger JohanssonThe Swedish Partnership for Mental Health in Vastmanland, NSPH, Västerås, Sweden.
Lena LönnbergRegion Vastmanland - Uppsala University Centre for Clinical Research, Vastmanland Hospital Vasteras, Västerås, Sweden.
Marina ArkkukangasCentre for Clinical Research Sörmland, Uppsala University, Eskilstuna, Sweden.
Johnny PellasDepartment of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.
Mattias DambergDepartment of Public Health and Caring Sciences, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDepression is common in older adults and is related to reduced quality of life and functional ability as well as increased mortality and morbidity. Current guidelines recommend psychological treatments for the treatment of depression in adults. Studies show that about 30% of older adults with depression in Sweden receive pharmacological treatment and about 3% receive psychological treatment. However, a majority receive no treatment at all. There is a need for effective and scalable psychological treatment options for older adults with depression in primary care. Behavioural activation is an extensively evaluated, effective, and relatively simple treatment for depression that can be delivered by health care professionals without comprehensive training in psychological treatment.

methodsWe will conduct a randomised controlled 2-armed parallel group multicentre trial comparing treatment as usual in primary care to a five-session telephone-delivered behavioural activation treatment as add on to treatment as usual. The current trial is open labelled. In all, 250 older adults (≥ 65 years) with depression will be recruited from primary healthcare centres in three Swedish regions. The primary outcome is depressive symptoms measured with the Montgomery Åsberg Depression Rating Scale - Self rating version (MADRS-S) after treatment and at 3- and 6-month follow-up. Secondary outcomes include depression diagnoses, activity level (self-rated and measured with accelerometer), and self-rated anxiety, daily functioning, quality of life, self-efficacy, and loneliness. DISCUSSION: There is a need for fully powered studies of brief behavioural activation for older adults with depression delivered by telephone in a primary care context. This study has the potential to improve first-line treatment of depression in older adults in primary care, consequently reducing morbidity and mortality within this population. Increasing the availability and accessibility to effective psychological treatment for depression in older adults is needed to meet future demographic changes.

trial registrationClinicalTrials.gov: NCT06284889 . Registered February 28, 2024.

Indexed as

DepressionMulticenter Studies as TopicPrimary Health CareRandomized Controlled Trials as TopicTelephoneAgedAge FactorsBehavior TherapyFemaleHumansMaleQuality of LifeSwedenTime FactorsTreatment OutcomeBehavioural activationDepressionDepressive symptomsGeriatricsOlder adultsPrimary care

Identifiers

PMID39369239
PMCPMC11453080

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.