Evidence map›Paper›PMID 39369190›Full record

ArticleBMC psychiatry2024

Study protocol TransTAM: Transdiagnostic research into emotional disorders and cognitive-behavioral therapy of the adaptive mind.

Andrea Hermann, Christoph Benke, Carlo R Blecker, Benjamin de Haas, Yifei He, Stefan G Hofmann, Jona R Iffland, Johanna Jengert-Stahl, Tilo Kircher, Katrin Leinweber and 14 more

Abstract readClinical Trial Protocol
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC psychiatry, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Andrea HermannDepartment of Psychotherapy and Systems Neuroscience, Justus Liebig University of Giessen, Giessen, Germany. andrea.hermann@psychol.uni-giessen.de.
Christoph BenkeDepartment of Clinical Psychology, Experimental Psychopathology and Psychotherapy, Philipps University of Marburg, Marburg, Germany.
Carlo R BleckerJustus Liebig University of Giessen, Bender Institute of Neuroimaging, Giessen, Germany.
Benjamin de HaasExperimental Psychology, Justus Liebig University of Giessen, Giessen, Germany.
Yifei HeDepartment of Psychiatry and Psychotherapy, Philipps University of Marburg, Marburg, Germany.
Stefan G HofmannDepartment of Psychology, Philipps University of Marburg, Marburg, Germany.
Jona R IfflandCenter of Psychiatry, Justus Liebig University of Giessen, Giessen, Germany.
Johanna Jengert-StahlDepartment of Psychotherapy and Systems Neuroscience, Justus Liebig University of Giessen, Giessen, Germany.
Tilo KircherDepartment of Psychiatry and Psychotherapy, Philipps University of Marburg, Marburg, Germany.
Katrin LeinweberDepartment of Psychiatry and Psychotherapy, Philipps University of Marburg, Marburg, Germany.
Marcel LinkaExperimental Psychology, Justus Liebig University of Giessen, Giessen, Germany.
Christoph MulertCenter of Psychiatry, Justus Liebig University of Giessen, Giessen, Germany.
Marie K NeudertDepartment of Psychotherapy and Systems Neuroscience, Justus Liebig University of Giessen, Giessen, Germany.
Ann-Kathrin NollDepartment of Psychotherapy and Systems Neuroscience, Justus Liebig University of Giessen, Giessen, Germany.
Christiane A MelzigDepartment of Clinical Psychology, Experimental Psychopathology and Psychotherapy, Philipps University of Marburg, Marburg, Germany.
Winfried RiefDepartment of Clinical Psychology, Philipps University of Marburg, Marburg, Germany.
Constantin RothkopfInstitute of Psychology, Centre for Cognitive Science, Technical University of Darmstadt, Darmstadt, Germany.
Axel SchäferJustus Liebig University of Giessen, Bender Institute of Neuroimaging, Giessen, Germany.
Christina V SchmitterDepartment of Psychiatry and Psychotherapy, Philipps University of Marburg, Marburg, Germany.
Verena SchusterDepartment of Psychology, Philipps University of Marburg, Marburg, Germany.
Rudolf StarkDepartment of Psychotherapy and Systems Neuroscience, Justus Liebig University of Giessen, Giessen, Germany.
Benjamin StraubeDepartment of Psychiatry and Psychotherapy, Philipps University of Marburg, Marburg, Germany.
Raphaela I ZimmerDepartment of Psychotherapy and Systems Neuroscience, Justus Liebig University of Giessen, Giessen, Germany.
Lukas KirchnerDepartment of Clinical Psychology, Philipps University of Marburg, Marburg, Germany.

Funding

German Research Foundation SFB/TRR393LOEWE Center DYNAMIC LOEWE1/16/519/03/09.001(0009)/98
6 · The paper itself

Abstract

backgroundEmotional disorders such as depression and anxiety disorders share substantial similarities in their etiology and treatment. In recent decades, these commonalities have been increasingly recognized in classification systems and treatment programs crossing diagnostic boundaries.

methodsTo examine the prospective effects of different transdiagnostic markers on relevant treatment outcomes, we plan to track a minimum of N = 200 patients with emotional disorders during their routine course of cognitive behavioral therapy at two German outpatient clinics. We will collect a wide range of transdiagnostic markers, ranging from basic perceptual processes and self-report measures to complex behavioral and neurobiological indicators, before entering therapy. Symptoms and psychopathological processes will be recorded before entering therapy, between the 20th and 24th therapy session, and at the end of therapy. DISCUSSION: Our results could help to identify transdiagnostic markers with high predictive power, but also provide deeper insights into which patient groups with which symptom clusters are less likely to benefit from therapy, and for what reasons.

trial registrationThe trial was preregistered at the German Clinical Trial Register (DRKS-ID: DRKS00031206; 2023-05-09).

Indexed as

Cognitive Behavioral TherapyAdultAnxiety DisordersDepressive DisorderFemaleGermanyHumansMaleProspective StudiesCognitive behavioral therapyLongitudinal studyNaturalistic outpatient sampleNeurobiological markersTherapy outcome predictionTherapy responseTransdiagnostic markersTransdiagnostic symptom dimensions

Identifiers

PMID39369190
PMCPMC11456249

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.