ArticleScientific reports2024
Comparison of a Scheimpflug imaging with other screening indices in diagnosing keratoconus and keratoconus suspect.
Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed.
- Prevalence of floppy eyelid syndrome and keratoconus in Egyptian patients with obstructive sleep apnea.International ophthalmology · 2026Article
- Multifactorial analysis of corneal biomechanical stability after deep anterior lamellar keratoplasty: integration of anterior segment imaging indices and ocular response analyzer data.American journal of translational research · 2026Article
- Artificial Intelligence-Derived Biomechanical Index for Early Corneal Ectasia Detection: Advancing Beyond Tomography.Ophthalmology science · 2026Article
- Analysis of astigmatism type influence onFrontiers in bioengineering and biotechnology · 2026Article
- Keratoconus prevalence in astigmatic adolescents: findings from a nationwide screening setting.Eye (London, England) · 2025Article
- Evaluating the Rate and Causes of Non-candidacy After Laser-Assisted in Situ Keratomileusis (LASIK) Screening.Cureus · 2025Article
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Authors and funding
7 authors.
Funding
Abstract
Keratoconus (KC) is an irreversible blinding eye disease; therefore, early screening of KC suspects (KCS) is crucial for protecting patients' quality of life. Scheimpflug imaging is a commonly used screening device in clinical practice. We aimed to evaluate the diagnostic ability of a Scheimpflug imaging device (Scansys) for KC and KCS and compared it with other Scheimpflug-based devices (Pentacam and Corvis ST). This prospective case-control study included 107 normal eyes, 72 KCS, and 57 KC. Scansys screening index Keratoconus probability (KCP) showed excellent performance in diagnosing KC at a cutoff value of 16.4 (area under the receiver operating characteristic [AUROC] = 1.000), with 100% sensitivity and 98.11% specificity. KCP had a better KCS diagnostic ability at a cutoff value of 8.9 (AUROC = 0.813) than Corvis biomechanical index (CBI, AUROC = 0.764), reaching 67.61% sensitivity and 85.85% specificity. Pentacam screening index Belin/Ambrósio enhanced ectasia display deviation (BAD-D) showed the best performance with 92.96% sensitivity and 89.62% specificity at a cutoff value of 1.525 (AUROC = 0.970) in diagnosing KCS. Scansys provides accurate KCP parameters in diagnosing KC; however, the efficiency of diagnosing KCS should be further optimized.
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Registered trials
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