Evidence map›Paper›PMID 39369074›Full record

ArticlePediatric surgery international2024

National centralization of Hirschsprung's disease in Sweden: a comparison of postoperative outcome.

Linnea Söderström, Christina Graneli, Daniel Rossi, Kristine Hagelsteen, Anna Gunnarsdottir, Jenny Oddsberg, Pär-Johan Svensson, Helena Borg, Matilda Bräutigam, Elisabet Gustafson and 3 more

Abstract readComparative Study
In one paragraph

Article in Pediatric surgery international, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Linnea SöderströmDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden. linnea.soderstrom@ki.se.
Christina GraneliDepartment of Pediatric Surgery, Skåne University Hospital Lund, Lund, Sweden.
Daniel RossiDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Kristine HagelsteenDepartment of Pediatric Surgery, Skåne University Hospital Lund, Lund, Sweden.
Anna GunnarsdottirDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Jenny OddsbergDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Pär-Johan SvenssonDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Helena BorgDepartment of Pediatric Surgery, Queen Silvia's Children's Hospital, Gothenburg, Sweden.
Matilda BräutigamDepartment of Pediatric Surgery, Queen Silvia's Children's Hospital, Gothenburg, Sweden.
Elisabet GustafsonDepartment of Pediatric Surgery, University Children's Hospital, Uppsala, Sweden.
Anna Löf GranströmDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.
Pernilla StenströmDepartment of Pediatric Surgery, Skåne University Hospital Lund, Lund, Sweden.
Tomas WesterDepartment of Women's and Children's Health, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIn Sweden, surgical treatment of Hirschsprung's disease (HSCR) was centralized from four to two pediatric surgery centers 1st of July 2018. In adults, centralization of surgical care for complex or rare diseases seems to improve quality of care. There is little evidence supporting centralization of pediatric surgical care. The aim of this study was to assess surgical management and postoperative outcome in HSCR patients following centralization of care.

methodsThis study retrospectively analyzed data of patients with HSCR that had undergone pull-through at a pediatric surgery center in Sweden from 1st of July 2013 to 30th of June 2023. Patients managed from 1st of July 2013 to 30th of June 2018 (before centralization) were compared with patients managed from 1st of July 2018 to 30th of June 2023 (after centralization) regarding surgical treatment, unplanned procedures under general anesthesia or readmissions up to 90 days after pull-through as well as complications classified according to Clavien-Madadi up to 30 days after pull-through.

resultsIn the 5-year period prior to centralization, 114 individuals from 4 treating centers were included and compared to 83 patients from 2 treating centers in the second period. There was no difference regarding age at pull-through or proportion of patients with a stoma prior to pull-through. An increase of laparoscopically assisted endorectal pull-through (8.8% to 39.8%) was observed (p < 0.001). No significant differences were seen in postoperative hospital stay, unplanned procedures under general anesthesia, or readmissions up to 90 days after pull-through. There was no difference in severe complications (Clavien-Madadi ≥ 3); however, HAEC treated with antibiotics increased following centralization (10.5-24.1%; p = 0.018).

conclusionCentralization of care for HSCR does not seem to delay time to pull-through nor reduce severe complications, unplanned procedures under general anesthesia or readmissions up to 90 days after pull-through. The increased HAEC rate may be due to increased awareness of mild HAEC. LEVEL OF EVIDENCE: Level III.

Indexed as

Hirschsprung DiseasePostoperative ComplicationsCentralized Hospital ServicesChildChild, PreschoolFemaleHumansInfantMalePatient ReadmissionRetrospective StudiesSwedenTreatment OutcomeCentralizationHirschsprung’s diseaseNational specialized medical carePostoperativeSurgical outcome

Identifiers

PMID39369074
PMCPMC11455800

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.