Evidence map›Paper›PMID 39368939›Full record

ArticleAmerican journal of surgery2025

Subsequent percutaneous breast biopsies after initial atypia diagnosis: The patient burden of long-term follow up.

Juliet C Dalton, Samantha M Thomas, Akiko Chiba, Ton Wang, E Shelley Hwang, Jennifer K Plichta

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In one paragraph

Article in American journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Juliet C DaltonDepartment of Surgery, Duke University Medical Center, 2301 Erwin Rd, Durham, NC 27707, USA.
Samantha M ThomasDuke Cancer Institute, Duke University, 10 Bryan Searle Drive, Durham, NC 27710, USA; Department of Biostatistics and Bioinformatics, Duke University, 40 Duke Medicine Circle, Durham, NC 27710, USA.
Akiko ChibaDepartment of Surgery, Duke University Medical Center, 2301 Erwin Rd, Durham, NC 27707, USA; Duke Cancer Institute, Duke University, 10 Bryan Searle Drive, Durham, NC 27710, USA.
Ton WangDepartment of Surgery, Duke University Medical Center, 2301 Erwin Rd, Durham, NC 27707, USA; Duke Cancer Institute, Duke University, 10 Bryan Searle Drive, Durham, NC 27710, USA.
E Shelley HwangDepartment of Surgery, Duke University Medical Center, 2301 Erwin Rd, Durham, NC 27707, USA; Duke Cancer Institute, Duke University, 10 Bryan Searle Drive, Durham, NC 27710, USA.
Jennifer K PlichtaDepartment of Surgery, Duke University Medical Center, 2301 Erwin Rd, Durham, NC 27707, USA; Duke Cancer Institute, Duke University, 10 Bryan Searle Drive, Durham, NC 27710, USA; Department of Population Health Sciences, Duke University Medical Center, 215 Morris St, Durham, NC 27701, USA. Electronic address: jennifer.plichta@duke.edu.

Funding

Women's Cancer Research ProgramP30CA014236 · NCI · DUKE UNIVERSITY · PI JOHN N. NORTON · 1985 to 2026
$174.8M
Building Interdisciplinary Research Careers in Women's Health (K12) - Administrative SupplementK12AR084231 · NIAMS · DUKE UNIVERSITY · PI Cindy Amundsen · 2023 to 2026
$2.5M
NCI NIH HHS P30 CA014236NIAMS NIH HHS K12 AR084231
6 · The paper itself

Abstract

backgroundBreast atypia increases overall breast cancer risk, potentially necessitating future interventions. This study examines the frequency and outcomes of additional percutaneous biopsies after an atypia diagnosis.

methodsAdult patients with breast atypia (atypical ductal hyperplasia, atypical lobular hyperplasia, lobular carcinoma in situ) at a single institution were reviewed for subsequent core needle biopsies (CNBs) and corresponding malignant outcomes.

resultsAmong 432 patients, median age at diagnosis was 54.8 ​y. Seventy-one (71/432, 16.4 ​%) patients developed a breast malignancy. During a median follow-up of 7.4 ​y, 113 patients underwent 149 additional CNBs. Twenty-six patients (26/113, 23.0 ​%) had >2 additional CNBs. Approximately half (79/149, 53.0 ​%) of all additional CNBs occurred within 5 years after breast atypia diagnosis.

conclusionA considerable number of patients with breast atypia undergo additional percutaneous biopsies, especially within 5 years post-atypia diagnosis. Our study highlights the significant burden of surveillance and the need for tailored follow-up strategies.

Indexed as

Breast NeoplasmsAdultAgedAged, 80 and overBiopsy, Large-Core NeedleBreastCarcinoma, Intraductal, NoninfiltratingFemaleFollow-Up StudiesHumansHyperplasiaMiddle AgedRetrospective StudiesAtypical ductal hyperplasiaAtypical lobular hyperplasiaBreast atypiaCore-needle biopsyLobular carcinoma in-situPercutaneous biopsy

Identifiers

PMID39368939
PMCPMC11835510

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.