Evidence map›Paper›PMID 39368737›Full record

ArticleChest2025

Relationship of Pulmonary Vascular Structure and Function With Exercise Capacity in Health and COPD.

Sophie É Collins, Miranda Kirby, Benjamin M Smith, Wan Tan, Jean Bourbeau, Stephanie Thompson, Sean van Diepen, Dennis Jensen, Sanja Stanojevic, Michael K Stickland and 1 more

Abstract read
In one paragraph

Article in Chest, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Sexually distinct multi-omic responses to progressive endurance exercise training in the rat lung.American journal of respiratory cell and molecular biology · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Sophie É CollinsDivision of Pulmonary Medicine, Faculty of Medicine and Dentistry University of Alberta, Edmonton, AB, Canada; Faculty of Rehabilitation Medicine, University of Alberta, Edmonton, AB, Canada.
Miranda KirbyDepartment of Physics, Toronto Metropolitan University, Toronto, ON, Canada.
Benjamin M SmithResearch Institute of the McGill University Health Centre and McGill University, Montreal, QC, Canada; Department of Epidemiology, Biostatistics, and Occupational Health, McGill University, Montreal, QC, Canada; Department of Medicine, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY.
Wan TanCentre for Heart Lung Innovation, Providence Health Care Research Institute, University of British Columbia, St. Paul's Hospital, Vancouver, BC, Canada.
Jean BourbeauResearch Institute of the McGill University Health Centre and McGill University, Montreal, QC, Canada.
Stephanie ThompsonDivision of Nephrology, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Sean van DiepenDivision of Critical Care, Faculty of Medicine and Dentistry, University of Alberta, Edmonton, AB, Canada.
Dennis JensenResearch Institute of the McGill University Health Centre and McGill University, Montreal, QC, Canada; Clinical Exercise and Respiratory Physiology Laboratory, Department of Kinesiology and Physical Education, McGill University, Montreal, QC, Canada.
Sanja StanojevicDepartment of Community Health and Epidemiology, Dalhousie University, Halifax, NS, Canada.
Michael K SticklandDivision of Pulmonary Medicine, Faculty of Medicine and Dentistry University of Alberta, Edmonton, AB, Canada; G.F. MacDonald Centre for Lung Health, Covenant Health, Edmonton, AB, Canada. Electronic address: michael.stickland@ualberta.ca.
CanCOLD Collaborative Research Group and the Canadian Respiratory Research Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAlthough it is generally accepted that aerobic exercise training does not change lung structure or function, some work suggests that greater pulmonary vascular structure and function are associated with higher exercise capacity (peak rate of oxygen consumption [V˙o RESEARCH QUESTION: Is there a cross-sectional association between the pulmonary vasculature and V˙o STUDY DESIGN AND

methodsParticipants from the Canadian Cohort Obstructive Lung Disease (CanCOLD) study were categorized as follows: participants with normal spirometry who had never smoked (n = 263), participants with normal spirometry who had ever smoked (n = 407), and COPD: individuals with spirometric airflow obstruction (n = 334). Total vessel volume (TVV), volume for vessels < 5 mm

resultsGeneral linear regression models revealed that even after controlling for FEV

interpretationOur results suggest that pulmonary vascular structure and Dlco are independently associated with V˙o

Indexed as

Exercise ToleranceLungPulmonary Disease, Chronic ObstructiveAgedCanadaCross-Sectional StudiesExercise TestFemaleHumansMaleMiddle AgedOxygen ConsumptionPulmonary Diffusing CapacitySpirometryTomography, X-Ray ComputedCOPDexercise capacitypulmonary vascular volume

Identifiers

PMID39368737
PMCPMC11867894

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.