Evidence map›Paper›PMID 39368720›Full record

ArticleActa biomaterialia2024

An optical system for cellular mechanostimulation in 3D hydrogels.

Rahul Sreedasyam, Bryce G Wilson, Patricia R Ferrandez, Elliot L Botvinick, Vasan Venugopalan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Acta biomaterialia, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rahul SreedasyamDepartment of Biomedical Engineering, University of California Irvine, Irvine, CA 92697-2715, United States.
Bryce G WilsonDepartment of Chemical and Biomolecular Engineering, University of California Irvine, Irvine, CA 92697-2580, United States.
Patricia R FerrandezDepartment of Biomedical Engineering, University of California Irvine, Irvine, CA 92697-2715, United States.
Elliot L BotvinickDepartment of Biomedical Engineering, University of California Irvine, Irvine, CA 92697-2715, United States; Beckman Laser Institute, University of California Irvine, Irvine, CA 92697-3010, United States. Electronic address: ebotvini@uci.edu.
Vasan VenugopalanDepartment of Biomedical Engineering, University of California Irvine, Irvine, CA 92697-2715, United States; Department of Chemical and Biomolecular Engineering, University of California Irvine, Irvine, CA 92697-2580, United States; Beckman Laser Institute, University of California Irvine, Irvine, CA 92697-3010, United States. Electronic address: vvenugop@uci.edu.

Funding

A Biophotonics Platform for Mechanotransduction and Metabolic MicroscopyR01GM129426 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI VENUGOPALAN, VASAN · 2019 to 2022
$1.9M
NIGMS NIH HHS R01 GM129426
6 · The paper itself

Abstract

We introduce a method utilizing single laser-generated cavitation bubbles to stimulate cellular mechanotransduction in dermal fibroblasts embedded within 3D hydrogels. We demonstrate that fibroblasts embedded in either amorphous or fibrillar hydrogels engage in Ca

Indexed as

FibroblastsHydrogelsMechanotransduction, CellularCalcium SignalingHumansPolyvinyl AlcoholHydrogelsPolyvinyl Alcohol3D hydrogelsCavitation bubbleCellular mechanosignalingCellular mechanotransductionCollagenLaser microbeamPolyvinyl alcohol

Identifiers

PMID39368720
PMCPMC13037603

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.