Evidence map›Paper›PMID 39368677›Full record

ArticleJournal of structural biology2024

SAXS of murine amelogenin identifies a persistent dimeric species from pH 5.0 to 8.0.

Sebastian T Mergelsberg, Hoshin Kim, Garry W Buchko, Bojana Ginovska

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of structural biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sebastian T MergelsbergPacific Northwest National Laboratory, Richland, WA 99354, USA. Electronic address: sebastian.mergelsberg@pnnl.gov.
Hoshin KimPacific Northwest National Laboratory, Richland, WA 99354, USA.
Garry W BuchkoPacific Northwest National Laboratory, Richland, WA 99354, USA; School of Molecular Biosciences, Washington State University, Pullman, WA, USA.
Bojana GinovskaPacific Northwest National Laboratory, Richland, WA 99354, USA. Electronic address: bojana.ginovska@pnnl.gov.

Funding

Structural, spatial, and temporal features guiding amelogenins transformation of calcium phosphate into enamelR01DE015347 · NIDCR · BATTELLE PACIFIC NORTHWEST LABORATORIES · PI SHAW, WENDY J · 2005 to 2025
$8.2M
NIDCR NIH HHS R01 DE015347
6 · The paper itself

Abstract

Amelogenin is an intrinsically disordered protein essential to tooth enamel formation in mammals. Using advanced small angle X-ray scattering (SAXS) capabilities at synchrotrons and computational models, we revisited measuring the quaternary structure of murine amelogenin as a function of pH and phosphorylation at serine-16. The SAXS data shows that at the pH extremes, amelogenin exists as an extended monomer at pH 3.0 (R

Indexed as

AmelogeninScattering, Small AngleX-Ray DiffractionAnimalsHydrogen-Ion ConcentrationMicePhosphorylationProtein MultimerizationAmelogeninAmelogenesisAmelogeninBiomineralizationNanospheresPhosphoproteinsREMDSAXS

Identifiers

PMID39368677
PMCPMC12230978

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.