Evidence map›Paper›PMID 39368241›Full record

ReviewCurrent opinion in microbiology2024

Dissecting host-microbe interactions with modern functional genomics.

Baylee J Russell, Manasvi Verma, Nolan K Maier, Marco Jost

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Current opinion in microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Baylee J RussellDepartment of Microbiology, Harvard Medical School, Boston, MA, USA.
Manasvi VermaDepartment of Microbiology, Harvard Medical School, Boston, MA, USA.
Nolan K MaierDepartment of Microbiology, Harvard Medical School, Boston, MA, USA.
Marco JostDepartment of Microbiology, Harvard Medical School, Boston, MA, USA. Electronic address: marco_jost@hms.harvard.edu.

Funding

Capturing, quantifying, and understanding combinatorial effects in small molecule signalingDP2GM154152 · NIGMS · HARVARD MEDICAL SCHOOL · PI Marco Jost · 2023 to 2026
$2.5M
Deciphering the logic of glycolipid signaling at the host-microbiome interfaceR00GM130964 · NIGMS · HARVARD MEDICAL SCHOOL · PI JOST, MARCO · 2021 to 2023
$747k
Linking a prominent gut microbiome-derived metabolite to host proteostasisF32GM149112 · NIGMS · HARVARD MEDICAL SCHOOL · PI MAIER, NOLAN KENJI KWAISUN · 2023 to 2025
$235k
NIGMS NIH HHS DP2 GM154152NIGMS NIH HHS F32 GM149112NIGMS NIH HHS R00 GM130964
6 · The paper itself

Abstract

Interrogation of host-microbe interactions has long been a source of both basic discoveries and benefits to human health. Here, we review the role that functional genomics approaches have played in such efforts, with an emphasis on recent examples that have harnessed technological advances to provide mechanistic insight at increased scale and resolution. Finally, we discuss how concurrent innovations in model systems and genetic tools have afforded opportunities to interrogate additional types of host-microbe relationships, such as those in the mammalian gut. Bringing these innovations together promises many exciting discoveries ahead.

Indexed as

GenomicsHost Microbial InteractionsAnimalsBacteriaGastrointestinal MicrobiomeHost-Pathogen InteractionsHumans

Identifiers

PMID39368241
PMCPMC11609025

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.