Evidence map›Paper›PMID 39368187›Full record

ArticleWater research2024

Mixed contaminant exposure in tapwater and the potential implications for human-health in disadvantaged communities in California.

Kelly L Smalling, Kristin M Romanok, Paul M Bradley, Michelle L Hladik, James L Gray, Leslie K Kanagy, R Blaine McCleskey, Diana A Stavreva, Annika K Alexander-Ozinskas, Jesus Alonso and 14 more

Abstract read
In one paragraph

Article in Water research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Kelly L SmallingU.S. Geological Survey, Lawrenceville, NJ, USA. Electronic address: ksmall@usgs.gov.
Kristin M RomanokU.S. Geological Survey, Lawrenceville, NJ, USA.
Paul M BradleyU.S. Geological Survey, Columbia, SC, USA.
Michelle L HladikU.S. Geological Survey, Sacramento, CA, USA.
James L GrayU.S. Geological Survey, Lakewood, CO, USA.
Leslie K KanagyU.S. Geological Survey, Lakewood, CO, USA.
R Blaine McCleskeyU.S. Geological Survey, Boulder, CO, USA.
Diana A StavrevaNational Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Annika K Alexander-OzinskasSierra Streams Institute, Nevada City, CA, USA.
Jesus AlonsoClean Water Action/Clean Water Fund, Oakland, CA, USA.
Wendy AvilaCommunities for a Better Environment, Los Angeles, CA, USA.
Sara E BreitmeyerU.S. Geological Survey, Downingtown, PA, USA.
Roberto BustilloCommunities for a Better Environment, Los Angeles, CA, USA.
Stephanie E GordonU.S. Geological Survey, Kearneysville, WV, USA.
Gordon L HagerNational Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Rena R JonesNational Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Dana W KolpinU.S. Geological Survey, Iowa City, IA, USA.
Seth NewtonOffice of Research and Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA.
Peggy ReynoldsUniversity of California San Francisco, San Francisco, CA, USA.
John SloopORISE, Office of Research & Development, U.S. Environmental Protection Agency, Research Triangle Park, NC, USA.
Andria VenturaClean Water Action/Clean Water Fund, Oakland, CA, USA.
Julie Von BehrenUniversity of California San Francisco, San Francisco, CA, USA.
Mary H WardNational Cancer Institute, National Institutes of Health, Rockville, MD, USA.
Gina M SolomonUniversity of California San Francisco, San Francisco, CA, USA.

Funding

In vivo Imaging of Steroid/Nuclear Receptor FunctionZ01BC010308 · NCI · DIVISION OF BASIC SCIENCES - NCI · PI HAGER, GORDON · 1999 to 2008
$735k
Intramural NIH HHS Z01 BC010308Intramural NIH HHS Z99 CA999999
6 · The paper itself

Abstract

Water is an increasingly precious resource in California as years of drought, climate change, pollution, as well as an expanding population have all stressed the state's drinking water supplies. Currently, there are increasing concerns about whether regulated and unregulated contaminants in drinking water are linked to a variety of human-health outcomes particularly in socially disadvantaged communities with a history of health risks. To begin to address this data gap by broadly assessing contaminant mixture exposures, the current study was designed to collect tapwater samples from communities in Gold Country, the San Francisco Bay Area, two regions of the Central Valley (Merced/Fresno and Kern counties), and southeast Los Angeles for 251 organic chemicals and 32 inorganic constituents. Sampling prioritized low-income areas with suspected water quality challenges and elevated breast cancer rates. Results indicated that mixtures of regulated and unregulated contaminants were observed frequently in tapwater throughout the areas studied and the types and concentrations of detected contaminants varied by region, drinking-water source, and size of the public water system. Multiple exceedances of enforceable maximum contaminant level(s) (MCL), non-enforceable MCL goal(s) (MCLG), and other health advisories combined with frequent exceedances of benchmark-based hazard indices were also observed in samples collected in all five of the study regions. Given the current focus on improving water quality in socially disadvantaged communities, our study highlights the importance of assessing mixed-contaminant exposures in drinking water at the point of consumption to adequately address human-health concerns (e.g., breast cancer risk). Data from this pilot study provide a foundation for future studies across a greater number of communities in California to assess potential linkages between breast cancer rates and tapwater contaminants.

Indexed as

Drinking WaterWater Pollutants, ChemicalCaliforniaEnvironmental ExposureEnvironmental MonitoringHumansVulnerable PopulationsWater QualityWater SupplyDrinking WaterWater Pollutants, ChemicalCaliforniaContaminant mixturesDisadvantaged communitiesDrinking waterHealth-effectsTapwater

Identifiers

PMID39368187
PMCPMC12376194

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.